VATH Antibody

Code CSB-PA883414XA01HU
Size Pls inquire
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ATP6V1H Polyclonal antibody
Uniprot No. Q9UI12
Target Names ATP6V1H
Alternative Names Atp6v1h antibody; ATPase; H+ transporting; lysosomal 50/57kDa; V1 subunit H antibody; CGI 11 antibody; CGI11 antibody; EC 3.6.3.14 antibody; MSTP042 antibody; NBP1 antibody; Nef binding protein 1 antibody; Nef-binding protein 1 antibody; Protein VMA13 homolog antibody; SFD antibody; SFDalpha antibody; SFDbeta antibody; V ATPase subunit H antibody; V-ATPase 50/57 kDa subunits antibody; V-ATPase subunit H antibody; V-type proton ATPase subunit H antibody; Vacuolar ATP synthase subunit H antibody; Vacuolar proton pump subunit H antibody; Vacuolar proton pump subunit SFD antibody; VATH_HUMAN antibody; VMA13 antibody
Raised in Rabbit
Species Reactivity Homo sapiens (Human)
Immunogen Recombinant Homo sapiens (Human) VATH protein
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (14-16 weeks)

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Earn $30 Amazon Card or 20μL/μg CUSABIO Trial Size Antibody. Details of rewards >>

Target Background

Function
(From Uniprot)
Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes.
Gene References into Functions
  1. These data provide evidence that partial loss of ATP6V1H function results in osteoporosis/osteopenia. PMID: 27924156
  2. These studies have uncovered a new, ATP6V1H-mediated pathway that regulates bone formation, and defines a new mechanism of disease that leads to bone loss. We propose that MMP9/MMP13 could be therapeutic targets for patients with this rare genetic disease. PMID: 28158191
  3. ATP6V1H may represent a critical molecular mechanism involved in the development of type 2 diabetes and its compilations through its important regulatory effect on vacuolar-ATPase activity. PMID: 21871445
  4. Our study shows that multiple mechanisms of pump dysfunction result from B1 subunit mutations with a common outcome being defective assembly PMID: 18368028
Protein Families V-ATPase H subunit family
Tissue Specificity Widely expressed.
Database Links

HGNC: 18303

OMIM: 608861

KEGG: hsa:51606

STRING: 9606.ENSP00000352522

UniGene: Hs.491737

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

© 2007-2021 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1