VDAC3 Antibody

Code CSB-PA882912XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) VDAC3 Polyclonal antibody
Uniprot No.
Target Names
VDAC3
Alternative Names
VDAC3 antibody; HSR2 antibody; At5g15090 antibody; F2G14.210Mitochondrial outer membrane protein porin 3 antibody; Protein HYPERSENSITIVE RESPONSE 2 antibody; Athsr2 antibody; Voltage-dependent anion-selective channel protein 3 antibody; AtVDAC3 antibody; VDAC-3 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana VDAC3 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
Gene References into Functions
  1. VDAC3 has a large conductance and is open at or around 0 mV and closes at positive or negative voltages.VDAC3 exhibits both fast and slow kinetics. PMID: 25686492
  2. Alternative cleavage and polyadenylation produces two major isoforms of VDAC3; the longest mRNA is targeted to the mitochondrial surface PMID: 24889622
  3. AtVDAC3 is in abundance in plasma membrane. PMID: 22294207
  4. VDAC3 expression is low compared with other VDAC members and its knockout mutant does not show any clear phenotype. PMID: 21705391
  5. The plant-specific kinesin, KP1, specifically interacts with VDAC3 on the mitochondrial outer membrane and that both KP1 and VDAC3 regulate aerobic respiration during seed germination at low temperature. PMID: 21406623

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Subcellular Location
Cell membrane. Mitochondrion outer membrane.
Protein Families
Eukaryotic mitochondrial porin (TC 1.B.8.1) family
Tissue Specificity
Expressed in leaf tips, anthers and stigma.
Database Links

KEGG: ath:AT5G15090

STRING: 3702.AT5G15090.1

UniGene: At.24654

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