wnt5b Antibody

1. the chaperon Wls and its ligands Wnt9a and Wnt5b are expressed in the ectoderm, whereas juxtaposed chondrocytes express Frzb and Gpc4. PMID: 27287801
2. disruption of wls resulted in a significant loss of craniofacial bone, whereas lack of gpc4, wnt5b and wnt9a resulted in severely delayed endochondral ossification. PMID: 27908786
3. novel mechanism for Wnt5b and Gpc4 regulation of chondrocyte behavior that is independent of the core Wnt/PCP molecules and differs from their collaborative action of controlling cell movements during gastrulation PMID: 26459057
4. In embryos overexpressing lbx1b, wnt5b, a ligand of the non-canonical Wnt/planar cell polarity (PCP) pathway, was significantly downregulated. PMID: 26820155
5. Swap70b and Def6a delineate Wnt11 and Wnt5b signalling pathways and have roles in convergent and extension cell movement during zebrafish gastrulation PMID: 24177263
6. CNBP up-regulates tbx2b and smarca5, and down-regulates wnt5b gene expression. PMID: 23667590
7. def6 morphants phenocopy Wnt5b mutants and ectopic overexpression of def6 essentially rescues Wnt5b morphants, indicating a novel role for def6 as a central GEF downstream of Wnt5b signaling PMID: 22039507
8. identify rgs3 as having an overlapping expression pattern with wnt5b in zebrafish and reveal that individual knockdown of either rgs3 or wnt5b gene function produces similar somite patterning defects. PMID: 20628572
9. Data suggest that full-length Ryk conveys Wnt5b signals in a directional manner during gastrulation. PMID: 20660632
10. Ppt/Wnt5 has a role in regulating cell shape and movement during zebrafish gastrulation PMID: 12676324
11. Data suggest that the Wnt-5 loss-of-function defect is consistent with calcium modulation having an antagonistic interaction with Wnt/beta-catenin signaling. PMID: 12952939
12. conserved role of a Wnt5/Fz2 signaling pathway in islet formation during pancreatic development. PMID: 16246260

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KEGG: dre:30105

STRING: 7955.ENSDARP00000106303

UniGene: Dr.389