isdA Antibody

Code CSB-PA763937ZA01SKW
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Product Details

Full Product Name
Rabbit anti-Staphylococcus aureus (strain MSSA476) isdA Polyclonal antibody
Uniprot No.
Target Names
isdA
Alternative Names
isdA antibody; frpA antibody; stbA antibody; SAS1064Iron-regulated surface determinant protein A antibody; Fur-regulated protein A antibody; Staphylococcal transferrin-binding protein A antibody
Raised in
Rabbit
Species Reactivity
Staphylococcus aureus
Immunogen
Recombinant Staphylococcus aureus isdA protein
Immunogen Species
Staphylococcus aureus (strain MSSA476)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Cell wall-anchored surface receptor that participates in the extraction of heme from oxidized methemoglobin/metHb to enable growth on hemoglobin as a sole iron source. Receives heme from IsdB and transfers it to IsdC. Plays also a role in the inhibition of host immune response. Protects S.aureus against the bactericidal protease activity of apolactoferrin. Enhances bacterial cellular hydrophobicity, which renders S.aureus resistant to bactericidal human skin fatty acids as well as to beta-defensins and cathelicidin. Also binds fibronectin and chains B-beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization.
Subcellular Location
Secreted, cell wall; Peptidoglycan-anchor.
Database Links

KEGG: sas:SAS1064

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