nadA Antibody

Code CSB-PA878213ZA01NGG
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Product Details

Full Product Name
Rabbit anti-Neisseria meningitidis serogroup B (strain MC58) nadA Polyclonal antibody
Uniprot No.
Target Names
nadA
Alternative Names
nadA antibody; NMB0394 antibody; Quinolinate synthase A antibody; EC 2.5.1.72 antibody
Raised in
Rabbit
Species Reactivity
Neisseria meningitidis serogroup B
Immunogen
Recombinant Neisseria meningitidis serogroup B nadA protein
Immunogen Species
Neisseria meningitidis serogroup B (strain MC58)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
Gene References into Functions
  1. Data show that a protective conformational epitope is located in the head of Neisserial adhesin A (NadA). PMID: 25404323
  2. The prevalence and genetic diversity of pilE and nadA were investigated in the prevalent serogroups and clonal complexes of N. meningitidis isolated in China. PMID: 23290624
  3. The authors demonstrate by reporter gene fusion assays that alterations of the FarR binding site within the nadA promoter are sufficient to induce transcription of nadA. PMID: 21292554
  4. Our results suggest that NadA expression is under both stochastic and tight environmental-sensing regulatory control PMID: 20041170
  5. NmFarR is a negative transcriptional regulator of the adhesin/invasin NadA. PMID: 19400792

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Subcellular Location
Cytoplasm.
Protein Families
Quinolinate synthase A family, Type 1 subfamily
Database Links

KEGG: nme:NMB0394

STRING: 122586.NMB0394

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