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Human Cardiotrophin-like cytokine factor 1(CLCF1) ELISA kit

Human Cardiotrophin-like cytokine factor 1(CLCF1) ELISA kit

Protocol MSDS

Code	CSB-EL005479HU
Size	96T,5×96T,10×96T
Price	Request a Quote or Start an on-line Chat
Trial Size	24T ELISA Kit Trial Size (Only USD$150/ kit) * The sample kit cost can be deducted from your subsequent orders of 96T full size kits of the same analyte at 1/5 per kit, until depleted in 6 months. Apply now

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Target Background

Product Details

Target Name

cardiotrophin-like cytokine factor 1

Alternative Names

B cell stimulating factor 3 ELISA Kit; B-cell-stimulating factor 3 ELISA Kit; BSF 3 ELISA Kit; BSF-3 ELISA Kit; BSF3 ELISA Kit; Cardiotrophin like cytokine ELISA Kit; Cardiotrophin like cytokine factor 1 ELISA Kit; Cardiotrophin-like cytokine factor 1 ELISA Kit; CISS 2 ELISA Kit; CISS2 ELISA Kit; CLC ELISA Kit; CLCF 1 ELISA Kit; Clcf1 ELISA Kit; CLCF1_HUMAN ELISA Kit; Cold induced sweating syndrome 2 ELISA Kit; CRLF 1 associated cytokine like factor 1 ELISA Kit; CRLF1 associated cytokine like factor 1 ELISA Kit; Neurotrophin 1 ELISA Kit; Neurotrophin 1/B cell stimulating factor 3 ELISA Kit; Neurotrophin1 ELISA Kit; NNT 1 ELISA Kit; NNT-1 ELISA Kit; Novel neurotrophin 1 ELISA Kit; Novel neurotrophin-1 ELISA Kit; NR 6 ELISA Kit; NR6 ELISA Kit

Abbreviation

CLCF1

Uniprot No.

Q9UBD9

Species

Homo sapiens (Human)

Sample Types

serum, plasma, cell culture supernates, tissue homogenates

Detection Range

0.312 ng/mL-20 ng/mL

Sensitivity

0.078 ng/mL

Assay Time

1-5h

Sample Volume

50-100ul

Detection Wavelength

450 nm

Research Area

Others

Assay Principle

quantitative

Measurement

Sandwich

ELISA Data Analysis

ELISA Standard Curve & Curve Expert software

Troubleshooting
and FAQs

ELISA kit FAQs

Storage

Store at 2-8°C. Please refer to protocol.

Lead Time

3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx

Description

This Human CLCF1 ELISA Kit was designed for the quantitative measurement of Human CLCF1 protein in serum, plasma, cell culture supernates, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 0.312 ng/mL-20 ng/mL and the sensitivity is 0.078 ng/mL.

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Target Background

Function
(From Uniprot)

In complex with CRLF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable). Also stimulates B-cells. Binds to and activates the ILST/gp130 receptor.

Gene References into Functions

CLF-1, based on its binding site for CLC and on two additional and independent sites for CNTFRalpha and sorLA, is a key player in CLC and CNTFRalpha signaling and turnover. PMID: 26858303
Cardiotrophin-like cytokine factor 1 (CLCF1) and neuropoietin (NP) signalling and their roles in development, adulthood, cancer and degenerative disorders. PMID: 26198769
albuminuria in focal segmental glomerulosclerosis is related to qualitative or quantitative changes in the CLCF1-CRLF1 complex. PMID: 25843671
activation of the Jak-STAT cascade is essential for corticotroph NNT-1/BSF-3 signaling. PMID: 12639901
Structural and docking interaction studies showed that the R197L substitution destabilized the contact site between CLC and CNTFRalpha. PMID: 16782820
Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain PMID: 18728012

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Involvement in disease

Cold-induced sweating syndrome 2 (CISS2)

Subcellular Location

Secreted.

Protein Families

IL-6 superfamily

Tissue Specificity

Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver.

Database Links

HGNC: 17412

OMIM: 607672

KEGG: hsa:23529

STRING: 9606.ENSP00000309338

UniGene: Hs.502977

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Human Cardiotrophin-like cytokine factor 1(CLCF1) ELISA kit

Product Details

Related Products

Customer Reviews and Q&A

Target Background