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Product Name:

Human Interleukin 18,IL-18 ELISA KIT

Product Type : ELISA Kit
Code : CSB-E07450h
Size : 96T
Uniprot NO. : Q14116
Abbreviation : IL18
Target Name : interleukin 18 (interferon-gamma-inducing factor)
Species : Human
Sample Types : serum, plasma, urine, tissue homogenates
Detect Range : 31.25 pg/ml-2000 pg/ml
Sensitivity : 7.8 pg/ml
Assay Time : 1-5h
Sample Volume : 50-100ul
Detection Wavelengt : 450 nm
Purity : >90% ( SDS-PAGE )
Research Area : Immunology
Protocol :
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Target details : This protein is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.[provided by RefSeq]
RGD : 2889
Reference :

1. Correlation of AIM2 expression in peripheral blood mononuclear cells from humans with acute and chronic hepatitis B,Wu DL et al,Hum Immunol,2013 May;74(5):514-21.

2. Increased intravitreous interleukin-18 correlated to vascular endothelial growth factor in patients with active proliferative diabetic retinopathy,Song Z et al,Graefes Arch Clin Exp Ophthalmol,2014 Feb 15.

3. The construction of three-dimensional micro-fluidic scaffolds of biodegradable polymers by solvent vapor based bonding of micro-molded layers.,Ryu W. et al,Biomaterials,2007

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