Human Interleukin 18,IL-18 ELISA KIT

Code CSB-E07450h
See More Details 24T ELISA kits trial application
Product Type ELISA Kit
Size 96T
Uniprot No. Q14116
Lead Time 3-5 working days
Abbreviation IL18
Target Name interleukin 18 (interferon-gamma-inducing factor)
Species Homo sapiens (Human)
Sample Types serum, plasma, urine, tissue homogenates
Detection Range 31.25 pg/mL-2000 pg/mL
Sensitivity 7.8 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Research Area Immunology
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details This protein is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.[provided by RefSeq]
RGD 2889
References
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Function Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
Subcellular Location Secreted
Protein Families IL-1 family
Database Links

HGNC: 5986

OMIM: 600953

KEGG: hsa:3606

STRING: 9606.ENSP00000280357

UniGene: Hs.83077

Pathway Inflammasome Signaling
NOD-like receptor signaling pathway

Q&A and Customer Reviews

Q&A
Q:

I am planning to carry out a study to assess level of Interleukin from Gingival Crevicular Fluid in Chronic Periodontitis patients before and after treatment.
Kindly provide the ELISA kit for analysis of Interleukin IL- 18. How many sample can be analysed by each kit ?

A:
Thanks for your inquiy. We have this kit available:
#CSB-E07450h,Human Interleukin 18,IL-18 ELISA KIT
It is based on sandwich enzyme immunoassay technique.For a 96T sandwich ELISA kit (doubleantibody), we suggest you run duplicates for the standard. In this way you can test 80 samples. We also suggest you run duplicates for
the sample, and in this way you can test 40 samples. You can decide how many kits you need according to the number of your samples. If you run a pre-test, the number of samples you can detect in one kit will be less.
If you want to test Gingival Crevicular Fluid, we suggest you do pre-testing first.
Q:

I have a question about your ELISA Kits for IL18. What are the difference between IL18 binding protein, IL18 receptor 1 and the IL 18 kit? I am working on the earlier stage of renal failure on diabetic patient. So I would like to know which Protein will be more sensitive and efficient for my research.

A:
Thanks for your inquiry.
IL18,IL18 binding protein, IL18 receptor 1 are in the IL18 family but they are different proteins.We checked some document related to the renal failure, there is much research on IL18 and IL18BP and you can consider this 2 proteins.
However, the occurrence of each disease is the result of multi-factor regulation. We suggest you check much more references and choose the proper one.
Q:

I am planning to carry out a study to assess level of Interleukin from Gingival Crevicular Fluid in Chronic Periodontitis patients before and after treatment.
Kindly provide the ELISA kit for analysis of Interleukin IL- 18. How many sample can be analysed by each kit ?

A:
Thanks for your inquiry.
#CSB-E07450h,Human Interleukin 18,IL-18 ELISA KIT
We have them all available.They are all appliedwith sandwich enzyme immunoassay technique.For a 96T sandwich ELISA kit (doubleantibody), we suggest you run duplicates for the standard. In this way you can test 80 samples. We also suggest you run duplicates for
the sample, and in this way you can test 40 samples. You can decide how many kits you need according to the number of your samples. If you run a pre-test, the number of samples you can detect in one kit will be less.
If you wan to test Gingival Crevicular Fluid ,we suggest you do pre-testing first.
Customer Reviews

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