Human Interleukin 18,IL-18 ELISA KIT

Code CSB-E07450h
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Product Type ELISA Kit
Size 96T
Uniprot No. Q14116
Abbreviation IL18
Target Name interleukin 18 (interferon-gamma-inducing factor)
Species Homo sapiens (Human)
Sample Types serum, plasma, urine, tissue homogenates
Detection Range 31.25 pg/mL-2000 pg/mL
Sensitivity 7.8 pg/mL
Assay Time 1-5h
Sample Volume 50-100ul
Detection Wavelength 450 nm
Availability 3-5 working days
Research Area Immunology
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Assay Principle quantitative
Measurement Sandwich
Target Details This protein is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.[provided by RefSeq]
RGD 2889
References
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Function Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
Subcellular Location Secreted
Protein Families IL-1 family
Database Links

HGNC: 5986

OMIM: 600953

KEGG: hsa:3606

STRING: 9606.ENSP00000280357

UniGene: Hs.83077

Pathway Inflammasome Signaling
NOD-like receptor signaling pathway

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