Recombinant Human Interleukin-18(IL18)

Code CSB-YP614514HU
Product Type Recombinant Protein
Size US$2010
Uniprot No. Q14116
Abbreviation IL18
Relevance Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias Iboctadekin Interferon gamma-inducing factor
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
Research Area Immunology
Source Yeast
Gene Names IL18
Protein Names Recommended name: Interleukin-18 Short name= IL-18 Alternative name(s): Iboctadekin Interferon gamma-inducing factor Short name= IFN-gamma-inducing factor Interleukin-1 gamma Short name= IL-1 gamma
Expression Region 37-193aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 20.2kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
Subcellular Location Secreted
Protein Families IL-1 family
Database Links

HGNC: 5986

OMIM: 600953

KEGG: hsa:3606

STRING: 9606.ENSP00000280357

UniGene: Hs.83077

Pathway Inflammasome Signaling
NOD-like receptor signaling pathway

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