All
  • All
  • ELISA Kit
  • Protein
  • Antibody
  • Molecular Biology Product
  • Small Molecule
  • Peptide
All
  • All
  • ELISA Kit
  • Protein
  • Antibody
  • Molecular Biology Product
  • Small Molecule
  • Peptide

Mouse CD48 antigen(CD48) ELISA kit

Promotion
Protocol
Code CSB-EL004941MO
Size 96T,5×96T,10×96T
Price Request a Quote
Trial Size 24T ELISA Kit Trial Size (Only USD$150/ kit)
* Sample kit cost can be deducted as a $30 credit for each 96-assay kit of the same analyte and brand you subsequently purchase within six months until depleted. More details >>
Interested in a trial size? Please leave a message below.
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Target Name
CD48 molecule
Alternative Names
Cd48 ELISA kit; Bcm-1CD48 antigen ELISA kit; BCM1 surface antigen ELISA kit; BLAST-1 ELISA kit; HM48-1 ELISA kit; MRC OX-45 surface antigen ELISA kit; SLAM family member 2 ELISA kit; SLAMF2 ELISA kit; Signaling lymphocytic activation molecule 2 ELISA kit; sgp-60 ELISA kit; CD antigen CD48 ELISA kit
Abbreviation
CD48
Uniprot No.
P18181
Species
Mus musculus (Mouse)
Detection Range
Request Information
Sensitivity
Request Information
Assay Time
1-5h
Sample Volume
50-100ul
Detection Wavelength
450 nm
Research Area
Immunology
Troubleshooting
and FAQs
ELISA kit FAQs
Storage
Store at 2-8°C. Please refer to protocol.
Shelf Life
6 months
Lead Time
3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.
Description

This mouse CD48 ELISA kit employs the quantitative sandwich enzyme immunoassay technique to measure the levels of mouse CD48 in multiple samples, including serum, plasma, or tissue homogenates. It also uses the enzyme-substrate chromogenic reaction to visualize and analyze the analyte levels through the color intensity. The intensity of the colored product is in direct proportion to the CD48 levels in the sample and is measured at 450 nm through a microplate reader.

CD48 is an adhesion and costimulatory molecule expressed constitutively on nearly all hematopoietic cells. It is involved in cell adhesion and costimulation, activation of immune cells, regulation of target cell lysis by cytolytic cells, as well as detection of microbes through its interaction with the bacterial component FimH. Through interactions with CD2, CD48 contributes to synapse organization between T cells and antigen-presenting cells (APCs) and can enhance TCR signaling. CD48 mediates interactions with T cells, B cells, and NK cells by binding to CD244. CD48 cross-linking on human eosinophils triggers the release of eosinophil granule proteins, cytokines, and chemokines.

Related Products

Cd48 Proteins

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
(From Uniprot)
Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
Gene References into Functions
  1. Molecular dynamic simulation explains unbinding and unfolding of CD48-2B4 protein complexes. PMID: 25142868
  2. These data demonstrate the important role of CD48 in SA/exotoxins-eosinophil activating interactions that can take place during allergic responses and indicate CD48 as a novel therapeutic target for allergy and especially of AD. PMID: 25255823
  3. ORMDL3 promotes eosinophil trafficking and activation via regulation of CD18, CD49d, and CD48. PMID: 24056518
  4. Ox-LDL significantly promoted the interaction of natural killer cells and dendritic cells via CD48-2B4 contact-dependent mechanisms. PMID: 21221603
  5. B6-specific background genes modulate the effect of CD48 on lupus nephritis in a recessive manner PMID: 21561736
  6. CD48 plays a vital role as an environmental sensor for regulating hematopoietic stem cells and progenitor cell numbers and inhibiting tumor development PMID: 21576698
  7. CD48 on surrounding NK or non-NK cells serves primarily as a ligand to stimulate 2B4 on the adjacent NK cells in mice PMID: 20647560
  8. CD48 interactions with NK cell receptor 2B4 among neighboring T cells during T cell priming augment CTL lysis of their specific targets. PMID: 12734329
  9. compare the relative contributions of MHC class I and CD48 to NK cell self-tolerance; and CD244 regulates NK cell tolerance to normal cells in vivo; evidence for MHC-independent NK self-recognition in a bone marrow rejection assay PMID: 15870174
  10. Cell surface receptors of the SLAM family, including CD150, CD244, and CD48, were differentially expressed among functionally distinct hematopoietic progenitor cells. PMID: 15989959
  11. Review of recent studies suggests an important role for interactions between 2B4 and CD48 in the course of T cell activation and proliferation PMID: 16081768
  12. T cell-induced experimental colitis is ameliorated only when CD48 is absent from both T cells and antigen-presenting cells. PMID: 16472597
  13. the mechanism of signal transduction by CD244 is to regulate FYN kinase recruitment and/or activity and the outcome of CD48/CD244 interactions is determined by which other receptors are engaged. PMID: 17599905

Show More

Hide All

Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Database Links
Promotions
Reward For Reviews
Free antibody trial
Contact Us

  Email: [email protected]
  Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Related Articles
DT3C, a Powerful Tool for ADC Drug Internalization In Vitro CD48: An Emerging Human Immune Co-stimulatory Molecule, Friend or Foe? Tetraspanin CD81: a Key Receptor for Hepatitis C Virus (HCV), an Established Exosome Marker, a Promising Target for Antiviral or Antitumor Research! ELISA Data Analysis How to Do The Pre-experiment before Your ELISA Experiment Four Types of ELISA 11 tips for choosing your right ELISA kit Do you Often Trouble in These Problems of ELISA? Problems and Solutions in ELISA Experiments
Related pathways
Natural killer cell mediated cytotoxicity Cell markers
CUSABIO guaranteed quality
icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of email
Email
[email protected]
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2025 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Privacy Policy
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*