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Mouse Prolactin/Luteotropic Hormone(PRL/LTH) ELISA Kit

Mouse Prolactin/Luteotropic Hormone(PRL/LTH) ELISA Kit

Citations (6) Protocol

Code	CSB-E06882m
Size	96T,5×96T,10×96T
Price	Request a Quote
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Product Details
Citations (6)
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Alternative Names

Prl ELISA Kit; Prolactin ELISA Kit; PRL ELISA Kit

Abbreviation

PRL

Uniprot No.

P06879

Species

Mus musculus (Mouse)

Sample Types

serum, plasma, tissue homogenates

Detection Range

0.8 ng/mL-28 ng/mL

Sensitivity

0.5 ng/mL

Assay Time

1-5h

Sample Volume

50-100ul

Detection Wavelength

450 nm

Research Area

Signal Transduction

Assay Principle

quantitative

Measurement

Competitive

Precision

Linearity

Recovery

Typical Data

ELISA Data Analysis

ELISA Standard Curve & Curve Expert software

Troubleshooting
and FAQs

ELISA kit FAQs

Storage

Store at 2-8°C. Please refer to protocol.

Shelf Life

6 months

Lead Time

3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx.

Description

The mouse prolactin (PRL) ELISA Kit is used to quantitatively measure PRL concentrations in mouse serum, plasma, or tissue homogenates. It performs well in important characteristics, including sensitivity, specificity, precision, recovery, linearity, and lot-to-lot consistency. This assay is based on the competitive ELISA mechanism and enzyme-substrate chromogenic reaction. The solution color develops inversely to the amount of PRL in the sample. And the intensity of the color can be measured at 450 nm via a microplate reader.

PRL is a sex hormone that is mainly synthesized and secreted by the lactotrophs of the pituitary and is responsible for the induction of lactation, the development of mammary alveoli, and milk production. It also exerts immunoregulatory properties. PRL signals by binding to PRL and activates a signaling cascade, including Jak/Stat, MAPK, Src, and PI3K/Akt pathways. PRL levels normally increase during pregnancy and breastfeeding and may rise due to physical stress, exercise, and certain medications and diseases. Higher-than-normal levels of PRL can cause certain symptoms, such as irregular periods, infertility, and erectile dysfunction.

Citations

Chronic pharmacologic manipulation of dopamine transmission ameliorates metabolic disturbance in trappc9-linked brain developmental syndrome Y Li,JCI insight,2024
Trappc9 deficiency causes obesity and fatty liver disease by constraining dopamine neurotransmission YW Xiong,/,2024
Lack of brain insulin receptor substrate-1 causes growth retardation, with decreased expression of growth hormone-releasing hormone in the hypothalamus. T Hayashi,Diabetes,2021
Short-term fastingDecreases excitatory synaptic inputs to ventromedial tuberoinfundibular dopaminergic neurons and attenuates their activity in male mice Kubota T.et al,Neurosci Lett,2018
Therapeutic Effect of Cuirutang on Maternal Rats with Hypogalactia Induced by Bromocriptine Dong Shiqi. et al,International Journal of Pharmacology ,2015
GATA4 Is a Critical Regulator of Gonadectomy-Induced Adrenocortical Tumorigenesis in Mice Krachulec J et al,Endocrinology,2012

Customer Reviews and Q&A

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Target Background

Function
(From Uniprot)

Prolactin acts primarily on the mammary gland by promoting lactation.

Subcellular Location

Secreted.

Protein Families

Somatotropin/prolactin family

Database Links

STRING: 10090.ENSMUSP00000105998

UniGene: Mm.1270

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Related pathways

Jak-STAT signaling pathway PI3K-Akt signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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Mouse Prolactin/Luteotropic Hormone(PRL/LTH) ELISA Kit

Product Details

Citations

Related Products

Customer Reviews and Q&A

Target Background