Recombinant Human Fibroblast growth factor 2 protein(FGF2) (Active)

Code CSB-AP002401HU
Product Type Growth Factor
Size Pls inquiry other sizesPurchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P09038
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias FGF-2, bFGF, Heparin-binding growth factor 2, HBGF-2
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 0.05 ng/ml, corresponding to a specific activity of >2.0x107 IU/mg.
Purity >96% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+PALPEDGGS GAFPPGHFKD PKRLYCKNGG FFLRIHPDGR VDGVREKSDP HIKLQLQAEE RGVVSIKGVC ANRYLAMKED GRLLASKCVT DECFFFERLE SNNYNTYRSR KYTSWYVALK RTGQYKLGSK TGPGQKAILF LPMSAKS
Research Area Cancer
Source E.Coli
Gene Names FGF2
Expression Region 143-288aa
Product Info Tag-Free
Mol. Weight 16.5 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3472745; 3780670; 2538817; 19054851; 15815621; 1785797; 2435575; 1721615; 8564983; 3579930; 2435284; 3964259; 3732516; 1417798; 1885605; 8663044; 10358027; 11509569; 11964394; 16257968; 18669637; 20230531; 15863030; 20094046; 22321063; 1769963; 1707542; 1
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Function Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Can induce angiogenesis
Subcellular location Secreted, Nucleus
Pathway MAPK signaling pathway
PI3K-Akt signaling pathway
Regulation of actin cytoskeleton
Ras signaling pathway
Signaling pathways regulating pluripotency of stem cells
Rap1 signaling pathway

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