FGF2

FGF2, also known as Fibroblast Growth Factor 2, is commonly referred to as basic fibroblast growth factor (bFGF). It plays a crucial role in various biological processes such as cell growth, proliferation, and differentiation. FGF2 exerts its effects by binding to fibroblast growth factor receptors (FGFRs) on the cell surface, activating downstream signaling pathways like the MAPK and PI3K - AKT pathways.
Altered FGF2 signaling has been associated with several diseases including cancer, cardiovascular diseases, and neurodegenerative disorders. In cancer, it can promote tumor angiogenesis. Regarding drug development, there are ongoing efforts to target FGF2 or its receptors. Some small - molecule inhibitors are under pre - clinical and clinical trials to block its activity and treat related diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

FGF2 Antibody (CSB-PA12849A0Rb)

Validated Data

Western blot
All lanes: FGF2 antibody at 4µg/ml
Lane 1: HepG2 whole cell lysate
Lane 2: Mouse heart tissue
Lane 3: Mouse liver tissue
Lane 4: Mouse lung tissue
Lane 5: Mouse kidney tissue
Lane 6: Mouse brain tissue
Lane 7: Mouse thymus tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 31, 23, 18, 22 kDa
Observed band size: 31 kDa

Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA12849A0Rb at dilution of 1:100

Immunohistochemistry of paraffin-embedded mouse lung tissue using CSB-PA12849A0Rb at dilution of 1:100

Human basic fibroblast growth factor,bFGF ELISA Kit (CSB-E08000h)

Validated Data

Code: CSB-E08000h

Size: 96T,5×96T,10×96T

Sensitivity: 0.39 pg/mL

Detection Range: 1.56 pg/mL-100 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following FGF2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

FGF2 Antibodies

FGF2 Proteins

FGF2 ELISA Kits

FGF2 Antibodies

FGF2 Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA06259A0Rb	Fgf2 Antibody	Mouse, Human	ELISA, WB
CSB-PA06259B0Rb	Fgf2 Antibody, HRP conjugated	Mouse	ELISA
CSB-PA06259C0Rb	Fgf2 Antibody, FITC conjugated	Mouse

FGF2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA12849C0Rb	FGF2 Antibody, FITC conjugated	Human
CSB-PA12849A0Rb	FGF2 Antibody	Human, Mouse	ELISA, WB, IHC
CSB-PA12849D0Rb	FGF2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA12849B0Rb	FGF2 Antibody, HRP conjugated	Human	ELISA
CSB-PA12847A0Rb	FGF2 Antibody	Human	ELISA, IHC
CSB-PA12847B0Rb	FGF2 Antibody, HRP conjugated	Human	ELISA
CSB-PA12847D0Rb	FGF2 Antibody, Biotin conjugated	Human	ELISA
CSB-PA006111	FGF2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA270018	FGF2 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA976397	FGF2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC

FGF2 Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA319495LA01RA	Fgf2 Antibody	Rat	ELISA, WB
CSB-PA319495LB01RA	Fgf2 Antibody, HRP conjugated	Rat	ELISA
CSB-PA319495LC01RA	Fgf2 Antibody，FITC conjugated	Rat
CSB-PA319495LD01RA	Fgf2 Antibody， Biotin conjugated	Rat	ELISA

FGF2 Proteins

FGF2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-BP008625MO CSB-EP008625MO CSB-MP008625MO CSB-EP008625MO-B	Recombinant Mouse Fibroblast growth factor 2 (Fgf2)	Baculovirus E.coli Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP008625MO	Recombinant Mouse Heparin-binding growth factor 2 protein (Fgf-2)	E.coli
CSB-AP004061MO	Recombinant Mouse Fibroblast growth factor 2 (Fgf2) (Active)	E.coli

FGF2 Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-EP008625SH CSB-BP008625SH CSB-MP008625SH CSB-EP008625SH-B	Recombinant Sheep Fibroblast growth factor 2 (FGF2)	E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FGF2 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP008625RB CSB-BP008625RB CSB-MP008625RB CSB-EP008625RB-B	Recombinant Rabbit Fibroblast growth factor 2 (FGF2), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FGF2 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-MP008625CH CSB-EP008625CH-B	Recombinant Chicken Fibroblast growth factor 2 (FGF2)	Mammalian cell In Vivo Biotinylation in E.coli

FGF2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-BP008625HU CSB-MP008625HU	Recombinant Human Fibroblast growth factor 2 (FGF2)	Baculovirus Mammalian cell
CSB-AP002401HU	Recombinant Human Fibroblast growth factor 2 (FGF2) (Active)	E.coli
CSB-EP008625HUa2	Recombinant Human Fibroblast growth factor 2 (FGF2)	E.coli
CSB-YP008625HU	Recombinant Human Fibroblast growth factor 2 (FGF2)	Yeast
CSB-AP003751HU	Recombinant Human Fibroblast growth factor 2 (FGF2), partial (Active)	E.coli
CSB-AP003831HU	Recombinant Human Fibroblast growth factor 2 (FGF2), partial (Active)	E.coli
CSB-AP003841HU	Recombinant Human Fibroblast growth factor 2 (FGF2) (Active)	E.coli
CSB-EP008625HU	Recombinant Human Heparin-binding growth factor 2 protein (FGFB)	E.coli
CSB-AP005911HU	Recombinant Human Basic Fibroblast Growth Factor (FGF2), partial (Active) (GMP)	E.Coli
CSB-EP008625HU-B	Recombinant Human Fibroblast growth factor 2 (FGF2),Biotinylated	E.coli
CSB-EP008625HU-WD	Recombinant Human Fibroblast growth factor 2 (FGF2) (Active)	E.coli

FGF2 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-BP008625BO CSB-MP008625BO CSB-EP008625BO-B	Recombinant Bovine Fibroblast growth factor 2 (FGF2)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FGF2 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP319495RA CSB-EP319495RA CSB-BP319495RA CSB-MP319495RA CSB-EP319495RA-B	Recombinant Rat Fibroblast growth factor 2 (Fgf2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP004171RA	Recombinant Rat Fibroblast growth factor 2 (Fgf2), partial (Active)	E.coli

FGF2 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP320077XBE CSB-EP320077XBE CSB-BP320077XBE CSB-MP320077XBE CSB-EP320077XBE-B	Recombinant Xenopus laevis Fibroblast growth factor 2 (fgf2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FGF2 Proteins for Monodelphis domestica (Gray short-tailed opossum)

Code	Product Name	Source
CSB-YP344550MUE CSB-EP344550MUE CSB-BP344550MUE CSB-MP344550MUE CSB-EP344550MUE-B	Recombinant Monodelphis domestica Fibroblast growth factor 2 (FGF2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FGF2 Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP692217EQV CSB-EP692217EQV CSB-BP692217EQV CSB-MP692217EQV CSB-EP692217EQV-B	Recombinant Pan troglodytes Fibroblast growth factor 2 (FGF2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FGF2 Proteins for Cavia porcellus (Guinea pig)

Code	Product Name	Source
CSB-YP713865GU CSB-EP713865GU CSB-BP713865GU CSB-MP713865GU CSB-EP713865GU-B	Recombinant Guinea pig Fibroblast growth factor 2 (FGF2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

FGF2 ELISA Kit

FGF2 ELISA Kit for Bos taurus (Bovine)

Code	Product Name	Sample Types	Sensitivity
CSB-EL008625BO	Bovine Heparin-binding growth factor 2(FGF2) ELISA kit	serum, plasma, tissue homogenates	1.56 pg/mL

FGF2 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E08000h	Human basic fibroblast growth factor,bFGF ELISA Kit	serum, plasma, tissue homogenates	0.39 pg/mL

FGF2 ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-E08001m	Mouse basic fibroblast growth factor,bFGF ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	0.78 pg/mL

FGF2 ELISA Kit for Sus scrofa (Pig)

Code	Product Name	Sample Types	Sensitivity
CSB-E12841p	Pig basic fibroblast growth factor,bFGF ELISA Kit	serum, plasma, tissue homogenates	1.2 pg/mL

FGF2 ELISA Kit for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Sample Types	Sensitivity
CSB-E06938Rb	Rabbit basic fibroblast growth factor,bFGF ELISA Kit	serum, plasma, tissue homogenates	1.95 pg/mL

FGF2 ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-E08002r	Rat basic fibroblast growth factor,bFGF ELISA Kit	serum, plasma, tissue homogenates	0.078 ng/ml

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FGF2

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