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Code | CSB-AP001651HU |
Size | $2618 |
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Purity | >95% as determined by SDS-PAGE and HPLC. |
Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
Activity | Fully biologically active when compared to standard. The ED50 as determined by inducing IL-8 secretion of human HepG2 cells is less than 1.0 μg/ml, corresponding to a specific activity of >1000 IU/mg. |
Target Names | IL17B |
Uniprot No. | Q9UHF5 |
Research Area | Immunology |
Alternative Names |
Cytokine like protein Zcyto7; Cytokine Zcyto7; IL 17B; IL 20 ; IL-17B; IL-20; IL17B; IL17B_HUMAN; IL20 ; Interleukin 17 beta; Interleukin 17B; Interleukin 20; Interleukin-17B; Interleukin-20; MGC138900; MGC138901; Neuronal interleukin 17 related factor ; Neuronal interleukin-17-related factor; NIRF ; ZCYTO7
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Species | Homo sapiens (Human) |
Source | E.Coli |
Expression Region | 21-180aa |
Complete Sequence | M+QPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F |
Mol. Weight | 18.3 kDa |
Protein Length | Full Length of Mature Protein |
Tag Info |
Tag-Free |
Form | Lyophilized powder |
Buffer | Lyophilized from a 0.2 µm filtered PBS, pH 7.4, with 0.1 % Tween-20 and 3 % Trehalose |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Troubleshooting and FAQs |
Protein FAQs |
Storage Condition | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Shelf Life | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
Lead Time | 5-10 business days |
Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
Datasheet & COA | Please contact us to get it. |
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Function |
Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.
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Gene References into Functions |
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Subcellular Location | Secreted. |
Protein Families | IL-17 family |
Tissue Specificity | Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary. |
Database Links |
HGNC: 5982 OMIM: 604627 KEGG: hsa:27190 STRING: 9606.ENSP00000261796 UniGene: Hs.156979 |