CCL2 Monoclonal Antibody

Datasheet
Code CSB-MA058641A0m
Product Type Monoclonal Antibody
Size US$350Purchase it in Cusabio online store
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Image
  • Immunohistochemical of paraffin-embedded human pancreas using CSB-MA058641A0m at dilution of 1:50

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human C-C motif chemokine 2
Raised in mouse
Species Reactivity Human
Specificity specific for human C-C motif chemokine 2 denatured and native forms
Tested Applications ELISA,IHC;Recommended dilution:IHC:1:50-1:500
Relevance Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. [1] "Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)."Furutani Y., Nomura H., Notake M., Oyamada Y., Fukui T., Yamada M., Larsen C.G., Oppenheim J.J., Matsushima K.Biochem. Biophys. Res. Commun. 159:249-255(1989) [2] "The human homolog of the JE gene encodes a monocyte secretory protein."Rollins B.J., Stier P., Ernst T., Wong G.G.Mol. Cell. Biol. 9:4687-4695(1989) [3] "Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE."Yoshimura T., Yuhki N., Moore S.K., Appella E., Lerman M.I., Leonard E.J.FEBS Lett. 244:487-493(1989)
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%,Protein G purified
Isotype IgG2b
Clonality monoclonal
Alias Monocyte chemoattractant protein 1,Monocyte chemotactic and activating factor,Monocyte chemotactic protein 1,Monocyte secretory protein JE,Small-inducible cytokine A2,CCL2,MCP1, SCYA2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 3D2E5
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