Your Good Partner in Biology Research
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Your Good Partner in Biology Research
| Code | CSB-AP003051HU |
| Product Type | Other |
| Size |
US$112Purchase it in Cusabio online store (only available for customers from the US) |
| Uniprot No. | P81534 |
| Lead Time | 5-10 business days |
| Image | |
| Storage Buffer | 0.2 μm filtered 20 mM PB, pH 7.4, 130 mM NaCl ,lyophilized |
| Alias | Beta-defensin 3, DEFB-3, HBD3, hBD-3, Defensin, beta 103 |
| Species | Homo sapiens (Human) |
| Biological_Activity | Fully biologically active when compared to standard. The ED50 as determined by anti-microbial activity against E.coli. is less than 30 μg/ml, corresponding to a specific activity of >33.3 IU/mg. |
| Purity | >98% as determined by SDS-PAGE and HPLC. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK |
| Research Area | Microbiology |
| Source | E.coli |
| Gene Names | DEFB103A |
| Expression Region | 23-67aa |
| Tag Info | Tag-Free |
| Mol. Weight | 5.2 kDa |
| Protein Description | Full Length of Mature Protein |
| PubMed ID | 11085990; 11702237; 11223260; 11741980 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. |
| Subcellular Location | Secreted |
| Protein Families | Beta-defensin family |
| Tissue Specificity | Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. |
| Database Links |
HGNC: 15967 OMIM: 606611 KEGG: hsa:414325 STRING: 9606.ENSP00000324633 UniGene: Hs.283082 |
DEFB103A Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP006663HU CSB-EP006663HU CSB-BP006663HU CSB-MP006663HU |
Recombinant Human Beta-defensin 103(DEFB103A) | Yeast E.coli Baculovirus Mammalian cell |
DEFB103A ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E14187h | Human β-defensins 3 ELISA Kit | serum, plasma, urine, cell culture supernates, tissue homogenates | 31.25 pg/mL |
Recombinant Rat Insulin-like growth factor-binding protein 1(Igfbp1)
Express system: E.coli
Species: Rattus norvegicus (Rat)
Recombinant Staphylococcus aureus Acyl carrier protein(acpP)
Express system: Yeast
Species: Staphylococcus aureus (strain Mu50 / ATCC 700699)
Recombinant Human ATP synthase subunit alpha, mitochondrial(ATP5F1A)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Cytotoxic T-lymphocyte protein 4(Ctla4),Partial
Express system: E.coli
Species: Mus musculus (Mouse)
