Code | CSB-AP003051HU |
Size |
US$112Purchase it in Cusabio online store (only available for customers from the US) |
Image |
Purity | >98% as determined by SDS-PAGE and HPLC. |
Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
Activity | Fully biologically active when compared to standard. The ED50 as determined by anti-microbial activity against E.coli. is less than 30 μg/ml, corresponding to a specific activity of >33.3 IU/mg. |
Target Names | DEFB103A |
Uniprot No. | P81534 |
Research Area | Microbiology |
Alternative Names | Beta-defensin 3, DEFB-3, HBD3, hBD-3, Defensin, beta 103 |
Species | Homo sapiens (Human) |
Source | E.coli |
Expression Region | 23-67aa |
Complete Sequence | GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK |
Mol. Weight | 5.2 kDa |
Protein Length | Full Length of Mature Protein |
Tag Info | Tag-Free |
Form | Lyophilized powder |
Buffer | Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 130 mM NaCl |
Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Troubleshooting and FAQs |
Protein FAQs |
Storage Condition | Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Shelf Life | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
Lead Time | Basically, we can dispatch the products out in 5-10 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week. |
Datasheet & COA | Please contact us to get it. |
Still Have Questions? | Leave a Message or Start an on-line Chat |
Function | Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. |
Subcellular Location | Secreted |
Protein Families | Beta-defensin family |
Tissue Specificity | Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. |
Database Links |
HGNC: 15967 OMIM: 606611 KEGG: hsa:414325 STRING: 9606.ENSP00000324633 UniGene: Hs.283082 |
Recombinant Human Peroxisomal biogenesis factor 19(PEX19) (Active)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Asialoglycoprotein receptor 1(Asgr1),partial
Express system: Yeast
Species: Mus musculus (Mouse)
Recombinant Human Proteasome subunit beta type-3(PSMB3)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Bovine Pulmonary surfactant-associated protein B(SFTPB),Partial
Express system: E.coli
Species: Bos taurus (Bovine)
Recombinant Human Cytochrome c-type heme lyase(HCCS)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Rat Dipeptidyl peptidase 4(Dpp4),partial
Express system: E.coli
Species: Rattus norvegicus (Rat)