Recombinant Human Uteroglobin protein(SCGB1A1) (Active)

Code CSB-AP000451HU
Product Type Other
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Uniprot No. P11684
Storage Buffer Lyophilized from a 0.2 ?m filtered concentrated solution in PBS, pH 7.4.
Alias Clara cell phospholipid-binding protein, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 μg/ml, corresponding to a specific activity of >200 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Research Area Immunology
Source E.Coli
Gene Names SCGB1A1
Expression Region 22-91aa
Tag Info Tag-Free
Mol. Weight 15.8 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3167058; 7733299; 14702039; 15489334; 1284526; 1400743; 1395029; 11788998; 7664082
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Function Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
Subcellular Location Secreted
Protein Families Secretoglobin family
Tissue Specificity Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).
Database Links

HGNC: 12523

OMIM: 192020

KEGG: hsa:7356

STRING: 9606.ENSP00000278282

UniGene: Hs.523732

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