Recombinant Mouse Cardiotrophin-1 protein(Ctf1) (Active)

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Code CSB-AP000531MO
Product Type Other
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q60753
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered 20 mM PB, pH 7.4, 150mM NaCl ,lyophilized
Alias CT-1
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF?1 cells is less than 0.5 ng/ml, corresponding to a specific activity of >2.0x106 IU/mg.
Purity >95% as determined by SDS?PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence MSQREGSLED HQTDSSISFL PHLEAKIRQT HNLARLLTKY AEQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSVLPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP GPEPVTVATL FTANSTAGIF SAKVLGFHVC GLYGEWVSRT EGDLGQLVPG GVA
Research Area Immunology
Source E.coli
Gene Names Ctf1
Expression Region 1-203aa
Tag Info Tag-Free
Mol. Weight 21.5 kDa
Protein Description Full Length
PubMed ID 7862649; 15489334
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Function Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
Subcellular Location Secreted
Protein Families IL-6 superfamily
Tissue Specificity Highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels in testis and brain. No expression in spleen.
Database Links

KEGG: mmu:13019

STRING: 10090.ENSMUSP00000049161

UniGene: Mm.389954

Pathway Jak-STAT signaling pathway

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