Recombinant Mouse Sonic hedgehog protein(Shh),partial (Active)

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Code CSB-AP000521MO
Product Type Other
Size US$112Purchase it in Cusabio online store
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Uniprot No. Q62226
Lead Time 5-10 business days
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Storage Buffer 0.2 μm filtered 20 mM PB, pH 7.4, 150mM NaCl ,lyophilized
Alias SHH, ,; Sonic hedgehog protein C-product Sonic hedgehog protein 27 kDa product,]
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by inducing alkaline phosphatase production of murine C3H10T1/2 cells is 0.5 - 1.0 μg/ml.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence GPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKITRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG
Research Area Cancer
Source E.coli
Gene Names Shh
Expression Region 26-198aa
Tag Info Tag-Free
Mol. Weight 19.8 kDa
Protein Description Partial
PubMed ID 7916661; 7720571; 16141072; 15489334; 7891723; 7736596; 8824192; 11486055; 14687547; 15075292; 16282375; 18081866; 7477329; 18794898; 19561611; 20519495
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Function Sonic hedgehog protein
Subcellular Location Sonic hedgehog protein N-product: Cell membrane, Lipid-anchor
Protein Families Hedgehog family
Tissue Specificity Expressed in a number of embryonic tissues including the notochord, ventral neural tube, floor plate, lung bud, zone of polarizing activity and posterior distal mesenchyme of limbs. In the adult, expressed in lung and neural retina.
Database Links

KEGG: mmu:20423

STRING: 10090.ENSMUSP00000002708

UniGene: Mm.57202

Pathway Hedgehog signaling pathway

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