ABCB1 Antibody

Datasheet
Code CSB-PA11737A0Rb
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Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P08183
Image
  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA11737A0Rb at dilution of 1:50

  • Immunofluorescent analysis of HepG2 cells using CSB-PA11737A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA11737A0Rb at dilution of 1:100

Immunogen Recombinant Human Multidrug resistance protein 1 protein (236-297AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Relevance Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Multidrug resistance protein 1 (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD antigen CD243), ABCB1, MDR1 PGY1
Immunogen Species Human
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Research Area Signal Transduction
Target Names ABCB1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Involvement in disease Inflammatory bowel disease 13 (IBD13)
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
Tissue Specificity Expressed in liver, kidney, small intestine and brain.
Database Links

HGNC: 40

OMIM: 171050

KEGG: hsa:5243

STRING: 9606.ENSP00000265724

UniGene: Hs.489033

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