ABCB1 Antibody

Code CSB-PA11737A0Rb
See More Details Free Antibody trial simple
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Uniprot No. P08183
  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA11737A0Rb at dilution of 1:50

  • Immunofluorescent analysis of HepG2 cells using CSB-PA11737A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA11737A0Rb at dilution of 1:100

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Immunogen Recombinant Human Multidrug resistance protein 1 protein (236-297AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Relevance Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Multidrug resistance protein 1 (EC (ATP-binding cassette sub-family B member 1) (P-glycoprotein 1) (CD antigen CD243), ABCB1, MDR1 PGY1
Immunogen Species Human
Research Area Signal Transduction
Target Names ABCB1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Involvement in disease Inflammatory bowel disease 13 (IBD13)
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily
Tissue Specificity Expressed in liver, kidney, small intestine and brain.
Database Links

HGNC: 40

OMIM: 171050

KEGG: hsa:5243

STRING: 9606.ENSP00000265724

UniGene: Hs.489033

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