ABCB7 Antibody

Datasheet
Code CSB-PA001053LA01HU
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Size US$299
Uniprot No. O75027
Image
  • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA001053LA01HU at dilution of 1:100

Immunogen Recombinant Human ATP-binding cassette sub-family B member 7, mitochondrial protein (23-140AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Relevance Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein), ABCB7, ABC7
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Research Area Signal Transduction
Target Names ABCB7
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Involvement in disease Anemia, sideroblastic, spinocerebellar ataxia (ASAT)
Subcellular Location Mitochondrion inner membrane, Multi-pass membrane protein
Protein Families ABC transporter superfamily, ABCB family, Heavy Metal importer (TC 3.A.1.210) subfamily
Database Links

HGNC: 48

OMIM: 300135

KEGG: hsa:22

STRING: 9606.ENSP00000253577

UniGene: Hs.370480

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