ABCG1 Antibody

Datasheet
Code CSB-PA001080LA01HU
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Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P45844
Image
  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA001080LA01HU at dilution of 1:100

Immunogen Recombinant Human ATP-binding cassette sub-family G member 1 protein (84-222AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Relevance Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog), ABCG1, ABC8 WHT1
Immunogen Species Human
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Research Area Neuroscience
Target Names ABCG1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein
Protein Families ABC transporter superfamily, ABCG family, Eye pigment precursor importer (TC 3.A.1.204) subfamily
Tissue Specificity Expressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease.
Database Links

HGNC: 73

OMIM: 603076

KEGG: hsa:9619

STRING: 9606.ENSP00000354995

UniGene: Hs.124649

Pathway Lipids and Inflammation in Atherogenesis

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