ACAA2 Antibody

Code CSB-PA297340
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA297340(ACAA2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA297340(ACAA2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: NIH/3T3 cells, A172 cells, human liver cancer tissue, Primary antibody: CSB-PA297340(ACAA2 Antibody) at dilution 1/375, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details

Uniprot No.
Target Names
ACAA2
Alternative Names
3 ketoacyl CoA thiolase antibody; 3 ketoacyl CoA thiolase mitochondrial antibody; 3-ketoacyl-CoA thiolase, mitochondrial antibody; 3-oxoacyl-CoA thiolase, mitochondrial antibody; ACAA 2 antibody; Acaa2 antibody; Acetyl CoA acyltransferase 2 antibody; Acetyl CoA acyltransferase antibody; Acetyl Coenzyme A acyltransferase 2 antibody; Acetyl-CoA acyltransferase antibody; Beta ketothiolase antibody; Beta-ketothiolase antibody; DSAEC antibody; Mitochondrial 3 oxoacyl CoA thiolase antibody; Mitochondrial 3 oxoacyl Coenzyme A thiolase antibody; Mitochondrial 3-oxoacyl-CoA thiolase antibody; T1 antibody; THIM_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human ACAA2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies. Also displays hydrolase activity on various fatty acyl-CoAs. Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation. Abolishes BNIP3-mediated apoptosis and mitochondrial damage.
Gene References into Functions
  1. ACAA2 is a functional BNIP3 binding partner and provide a possible linkage between fatty acid metabolism and apoptosis of cells. PMID: 18371312
Subcellular Location
Mitochondrion.
Protein Families
Thiolase family
Database Links

HGNC: 83

OMIM: 604770

KEGG: hsa:10449

STRING: 9606.ENSP00000285093

UniGene: Hs.200136

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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