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| Code | CSB-RA978277A0HU |
| Size | US$210 |
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| Application | Recommended Dilution |
|---|---|
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
| IF | 1:50-1:200 |
The ACAA2 recombinant monoclonal antibody is produced through genetic engineering by cloning and expressing the ACAA2 monoclonal antibody-encoding gene. To generate the ACAA2 monoclonal antibody, a synthesized peptide derived from human ACAA2 protein was used as an immunogen. Affinity chromatography is employed to purify the obtained ACAA2 recombinant monoclonal antibody, ensuring high purity. This ACAA2 recombinant monoclonal antibody specifically recognizes and binds to the ACAA2 protein and has been validated for use in human samples. Its quality and specificity were tested through multiple applications such as ELISA, WB, IHC, and IF.
The ACAA2 protein mainly catalyzes the beta-oxidation of fatty acids in the mitochondria, which involves the degradation of fatty acids to generate energy for various cellular processes. ACAA2 specifically catalyzes the formation of acetyl-CoA from long-chain acyl-CoA substrates, which is essential for fatty acid oxidation and energy metabolism. Additionally, ACAA2 plays a critical role in the regulation of lipid metabolism, lipid droplet formation, and lipid signaling pathways. Mutations in ACAA2 have been associated with various metabolic disorders, including hypoglycemia, hyperammonemia, and Reye syndrome.
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