ADAM29 Antibody

Code CSB-PA986639
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA986639(ADAM29 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA986639(ADAM29 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
ADAM29
Alternative Names
A disintegrin and metalloproteinase domain 29 antibody; ADA29_HUMAN antibody; ADAM 29 antibody; ADAM metallopeptidase domain 29 antibody; ADAM29 antibody; Cancer/testis antigen 73 antibody; CT73 antibody; Disintegrin and metalloproteinase domain-containing protein 29 antibody; Metallaproteinase disintegrin (ADAM29) antibody; svph1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human ADAM29
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein.
Gene References into Functions
  1. Increased transcript expression of ADAM29 was observed in breast cancer tissues compared to normal ones. The expression of ADAM29 and its mutations in different domains significantly influenced proliferation, migration and invasion of breast cancer cells in vitro. PMID: 26977022
  2. PCMC expression of ADAM29, FLRT2, and SLC18A3 could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations PMID: 24732660
  3. mutated ADAM27 and ADAM7 genes could play a role in melanoma progression. PMID: 21618342
  4. quantification of LPL and ADAM29 gene expression is a strong prognostic indicator in CLL, providing better prognostic assessment than ZAP-70 in advanced stages of the disease PMID: 15802535
  5. Results support the use of LPL and ADAM29 gene expression associated to IGHV mutational status for predicting the clinical outcome of patients treated by oral fludarabine + cyclophosphamide and could be considered for treatment strategies. PMID: 19340428

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Involvement in disease
Has been found to be frequently mutated in melanoma. ADAM7 mutations may play a role in melanoma progression and metastasis.
Subcellular Location
Membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed specifically in testes.
Database Links

HGNC: 207

OMIM: 604778

KEGG: hsa:11086

STRING: 9606.ENSP00000352177

UniGene: Hs.126838

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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