AKAP2 Antibody

Code CSB-PA010254
Size US$100
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Product Details

Uniprot No.
Target Names
AKAP2
Alternative Names
AKAP2 antibody; KIAA0920 antibody; PRKA2A-kinase anchor protein 2 antibody; AKAP-2 antibody; AKAP-KL antibody; Protein kinase A-anchoring protein 2 antibody; PRKA2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the N-terminal region of Human AKAP 2.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP.
Gene References into Functions
  1. study of the variants in AKAP2 gene did not support its association with the susceptibility of adolescent idiopathic scoliosis in the Chinese population. PMID: 28838314
  2. expression of AKAP2 was elevated in ovarian cancer. Furthermore, overexpression of AKAP2 promoted the growth and migration of ovarian cancer cells, whereas knockdown of AKAP2 expression reduced the growth and migration of ovarian cancer cells. PMID: 28849175
  3. AKAP2 was therefore implicated as a novel gene mutated in a Chinese family with adolescent idiopathic scoliosis. PMID: 26989089
  4. AKAP2 is expressed in human prostates, its expression is elevated in metastatic prostate cancer. PMID: 26432469
Database Links

HGNC: 372

OMIM: 604582

KEGG: hsa:11217

STRING: 9606.ENSP00000451476

UniGene: Hs.591908

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