ALDH6A1 Antibody

Code CSB-PA925196
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA925196(ALDH6A1 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA925196(ALDH6A1 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Rat kidney tissue, Primary antibody: CSB-PA925196(ALDH6A1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details

Uniprot No.
Target Names
ALDH6A1
Alternative Names
1110038I05Rik antibody; AI314632 antibody; Aldehyde dehydrogenase 6 family member A1 antibody; Aldehyde dehydrogenase family 6 member A1 antibody; Aldehyde dehydrogenase family 6, subfamily A1 antibody; ALDH6A1 antibody; Malonate semialdehyde dehydrogenase antibody; Malonate-semialdehyde dehydrogenase [acylating] antibody; Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody; Methylmalonate-semialdehyde dehydrogenase [acylating] antibody; MGC37325 antibody; MGC40271 antibody; Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody; mitochondrial antibody; MMSA_HUMAN antibody; MMSADHA antibody; MMSDH antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human ALDH6A1
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
Gene References into Functions
  1. Results show that ALDH6A1 expression is significantly reduced in metastatic prostate cancer and represents a strong marker predicting survival, along with HSP27 and prohibitin. PMID: 30396985
  2. ACAT1, ACACA, ALDH6A1 and MTHFD1 represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals. PMID: 25099943
  3. Mutation analysis in the ALDH6A1 gene can reveal a cause of 3-hydroxyisobutyric aciduria, which may present with only slightly increased urinary levels of 3-hydroxyisobutyric acid, if a patient is metabolically stable [case reports] PMID: 21863277
Involvement in disease
Methylmalonate semialdehyde dehydrogenase deficiency (MMSDHD)
Subcellular Location
Mitochondrion.
Protein Families
Aldehyde dehydrogenase family
Database Links

HGNC: 7179

OMIM: 603178

KEGG: hsa:4329

STRING: 9606.ENSP00000450436

UniGene: Hs.293970

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