ALDH6A1 Antibody

Code CSB-PA001578LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse kidney tissue, Mouse liver tissue
    All lanes: ALDH6A1 antibody at 2.5μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 58, 57 kDa
    Observed band size: 58 kDa

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001578LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ALDH6A1 Polyclonal antibody
Uniprot No.
Target Names
ALDH6A1
Alternative Names
1110038I05Rik antibody; AI314632 antibody; Aldehyde dehydrogenase 6 family member A1 antibody; Aldehyde dehydrogenase family 6 member A1 antibody; Aldehyde dehydrogenase family 6, subfamily A1 antibody; ALDH6A1 antibody; Malonate semialdehyde dehydrogenase antibody; Malonate-semialdehyde dehydrogenase [acylating] antibody; Methylmalonate semialdehyde dehydrogenase [acylating] mitochondrial antibody; Methylmalonate-semialdehyde dehydrogenase [acylating] antibody; MGC37325 antibody; MGC40271 antibody; Mitochondrial acylating methylmalonate semialdehyde dehydrogenase antibody; mitochondrial antibody; MMSA_HUMAN antibody; MMSADHA antibody; MMSDH antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial protein (274-399AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ALDH6A1 Antibody (Product code: CSB-PA001578LA01HU) is Non-conjugated. For ALDH6A1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA001578LB01HU ALDH6A1 Antibody, HRP conjugated ELISA
FITC CSB-PA001578LC01HU ALDH6A1 Antibody, FITC conjugated
Biotin CSB-PA001578LD01HU ALDH6A1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
Gene References into Functions
  1. Results show that ALDH6A1 expression is significantly reduced in metastatic prostate cancer and represents a strong marker predicting survival, along with HSP27 and prohibitin. PMID: 30396985
  2. ACAT1, ACACA, ALDH6A1 and MTHFD1 represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals. PMID: 25099943
  3. Mutation analysis in the ALDH6A1 gene can reveal a cause of 3-hydroxyisobutyric aciduria, which may present with only slightly increased urinary levels of 3-hydroxyisobutyric acid, if a patient is metabolically stable [case reports] PMID: 21863277
Involvement in disease
Methylmalonate semialdehyde dehydrogenase deficiency (MMSDHD)
Subcellular Location
Mitochondrion.
Protein Families
Aldehyde dehydrogenase family
Database Links

HGNC: 7179

OMIM: 603178

KEGG: hsa:4329

STRING: 9606.ENSP00000450436

UniGene: Hs.293970

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