ALX1 Antibody

1. According to our analysis, three proteins, namely aristaless-like homeobox1 isoform X1 (ALX1), major histocompatibility complex polypeptide-related sequence A (MICA), and uncharacterized protein C14orf105 isoform X12 were found to be potential markers for Opisthorchis viverrini (OV)- infection, as they were predominantly found in all OV-infected groups PMID: 29936472
2. Our study concludes that the splice site variant identified in the ALX1 gene causes mild form of Frontonasal dysplasia. PMID: 27324866
3. we identify critical roles of ALX1 in lung cancer development and progression PMID: 26722397
4. Knockdown of the CART1 gene significantly inhibited cell invasion and proliferation and induce cell cycle arrest in S phase. PMID: 27053613
5. we found that depletion of ALX1 caused a dramatic cell cycle arrest, followed by massive apoptotic cell death, and eventually resulted in a significant decrease in migration and invasion of the osteosarcoma cell line studied. PMID: 25736924
6. hypermethylation of HIST1H4F, PCDHGB6, NPBWR1, ALX1, and HOXA9 was significantly associated with shorter survival in stage 1 Non-small-cell lung cancer PMID: 24081945
7. ALX1 upregulated expression of the key EMT regulator Snail (SNAI1) and that it mediated EMT activation and cell invasion by ALX1. PMID: 23288509
8. Disruption of CART1 (ALX1) causes extreme microphthalmia and severe facial clefting. PMID: 20451171

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HGNC: 1494

OMIM: 601527

KEGG: hsa:8092

STRING: 9606.ENSP00000315417

UniGene: Hs.41683