AREG Antibody

Datasheet
Code CSB-PA11339A0Rb
See More Details Free Antibody trial simple
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Uniprot No. P15514
Image
  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA11339A0Rb at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA11339A0Rb at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA11339A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Immunogen Recombinant Human Amphiregulin protein (107-148AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Relevance Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Amphiregulin (AR) (Colorectum cell-derived growth factor) (CRDGF), AREG, AREGB SDGF
Immunogen Species Human
Research Area Signal Transduction
Target Names AREG
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Subcellular Location Membrane, Single-pass membrane protein
Protein Families Amphiregulin family
Database Links

HGNC: 651

OMIM: 104640

KEGG: hsa:374

STRING: 9606.ENSP00000370227

UniGene: Hs.270833

Pathway ErbB signaling pathway
Hippo signaling pathway
MAPK signaling pathway
PI3K-Akt signaling pathway

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