Recombinant Human Amphiregulin protein(AREG) (Active)

In Stock
Code CSB-AP002641HU
Product Type Growth Factor
Size US$112Purchase it in Cusabio online store
(Shop online in the US. Customers outside the US,
please order from local distributors.)
Uniprot No. P15514
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias AR, CRDGF
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is between 5-10 ng/ml.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK
Research Area Cancer
Source E.coli
Gene Names AREG
Expression Region 101-198aa
Tag Info Tag-Free
Mol. Weight 11.3 kDa
Protein Description Partial
PubMed ID 2325643; 15489334; 2466334; 3413110; 2017164; 1333777; 22967896; 7679104; 17607000;
Still Have Questions? Leave a Message or Start an on-line Chat
Function Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Subcellular Location Membrane, Single-pass membrane protein
Protein Families Amphiregulin family
Database Links

HGNC: 651

OMIM: 104640

KEGG: hsa:374

STRING: 9606.ENSP00000370227

UniGene: Hs.270833

Pathway ErbB signaling pathway
Hippo signaling pathway
MAPK signaling pathway
PI3K-Akt signaling pathway

Related Products

AREG Antibodies

AREG Antibodies for Homo sapiens (Human)

AREG Antibodies for Human

AREG Proteins

AREG Proteins for Homo sapiens (Human)

AREG ELISA Kit

AREG ELISA Kit for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.