ARHGAP15 Antibody

Datasheet

Code	CSB-PA002016GA01HU
Size	US$685
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Product Details

Uniprot No.	Q53QZ3
Target Names	ARHGAP15
Alternative Names	ARHGAP15 antibody; BM-024 antibody; BM-030 antibody; BM-046 antibody; Rho GTPase-activating protein 15 antibody; ArhGAP15 antibody; Rho-type GTPase-activating protein 15 antibody
Raised in	Rabbit
Species Reactivity	Human,Mouse,Rat
Immunogen	Human ARHGAP15
Immunogen Species	Homo sapiens (Human)
Isotype	IgG
Purification Method	Antigen Affinity Purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications	ELISA,WB,IHC
Protocols	ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Function	GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.
Gene References into Functions	ARHGAP15 rs4662344-T ssociation with diverticular disease in Iceland and Denmark population. PMID: 28585551 ARHGAP15 immunoreactivity correlated with decreased risk of recurrence and improved prognosis in breast carcinoma. ARHGA15 overexpression suppressed cell proliferation and migration of MCF-7 cells. PMID: 29534468 FOXP3 can regulate the expression of ARHGAP15 and affects migration of glioma cells through the Rac1 signaling pathway PMID: 27862679 ArhGAP15 plays a dual negative role in regulating small GTPase signaling, by acting at the level of the GTPase itself, as well interacting with its effector, Pak kinase. PMID: 23760270 ARHGAP15 is associated with acute lung injury in mice PMID: 21297076 a potential regulator of Rac1 PMID: 12650940 Show More Hide All
Subcellular Location	Cytoplasm, Membrane, Peripheral membrane protein
Tissue Specificity	Expressed in lung, liver and lymphoid cells.
Database Links	HGNC: 21030 OMIM: 610578 KEGG: hsa:55843 STRING: 9606.ENSP00000295095 UniGene: Hs.171011

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