ARHGAP15 Antibody

Code CSB-PA002016GA01HU
Size US$685
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Product Details

Uniprot No. Q53QZ3
Target Names ARHGAP15
Alternative Names ARHGAP15 antibody; BM-024 antibody; BM-030 antibody; BM-046 antibody; Rho GTPase-activating protein 15 antibody; ArhGAP15 antibody; Rho-type GTPase-activating protein 15 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ARHGAP15
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB,IHC
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction.
Gene References into Functions
  1. ARHGAP15 rs4662344-T ssociation with diverticular disease in Iceland and Denmark population. PMID: 28585551
  2. ARHGAP15 immunoreactivity correlated with decreased risk of recurrence and improved prognosis in breast carcinoma. ARHGA15 overexpression suppressed cell proliferation and migration of MCF-7 cells. PMID: 29534468
  3. FOXP3 can regulate the expression of ARHGAP15 and affects migration of glioma cells through the Rac1 signaling pathway PMID: 27862679
  4. ArhGAP15 plays a dual negative role in regulating small GTPase signaling, by acting at the level of the GTPase itself, as well interacting with its effector, Pak kinase. PMID: 23760270
  5. ARHGAP15 is associated with acute lung injury in mice PMID: 21297076
  6. a potential regulator of Rac1 PMID: 12650940

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Subcellular Location Cytoplasm, Membrane, Peripheral membrane protein
Tissue Specificity Expressed in lung, liver and lymphoid cells.
Database Links

HGNC: 21030

OMIM: 610578

KEGG: hsa:55843

STRING: 9606.ENSP00000295095

UniGene: Hs.171011


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