ARHGEF16 Antibody

Code CSB-PA008867
Size US$100
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Product Details

Uniprot No.
Target Names
ARHGEF16
Alternative Names
ARHGEF 16 antibody; ARHGEF16 antibody; ARHGG_HUMAN antibody; Ephexin 4 antibody; Ephexin-4 antibody; EPHEXIN4 antibody; GEF16 antibody; NBR antibody; Putative Neuroblastoma Protein antibody; Rho guanine exchange factor (GEF) 16 antibody; Rho guanine nucleotide exchange factor (GEF) 16 antibody; Rho guanine nucleotide exchange factor 16 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human ARHGEF16.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.
Gene References into Functions
  1. Sixty-four novel structural analogues of Y27632 were synthesized and tested for their ability to persistently inhibit the transformation of NIH3T3 cells by Rho guanidine exchange factor 16 (ARHGEF16) or Ras. PMID: 19707205
  2. These data suggest that HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation PMID: 21139582
  3. The ephexin4 protein mediates cell migration through a RhoG-dependent mechanism. PMID: 20679435
Subcellular Location
Cytoplasm.
Database Links

HGNC: 15515

KEGG: hsa:27237

STRING: 9606.ENSP00000367629

UniGene: Hs.87435

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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