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ARHGEF16 Antibody

Datasheet
Code CSB-PA002046GA01HU
Size US$685
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Product Details

Uniprot No. Q5VV41
Target Names ARHGEF16
Alternative Names ARHGEF 16 antibody; ARHGEF16 antibody; ARHGG_HUMAN antibody; Ephexin 4 antibody; Ephexin-4 antibody; EPHEXIN4 antibody; GEF16 antibody; NBR antibody; Putative Neuroblastoma Protein antibody; Rho guanine exchange factor (GEF) 16 antibody; Rho guanine nucleotide exchange factor (GEF) 16 antibody; Rho guanine nucleotide exchange factor 16 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ARHGEF16
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB,IHC
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6.
Gene References into Functions
  1. Sixty-four novel structural analogues of Y27632 were synthesized and tested for their ability to persistently inhibit the transformation of NIH3T3 cells by Rho guanidine exchange factor 16 (ARHGEF16) or Ras. PMID: 19707205
  2. These data suggest that HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation PMID: 21139582
  3. The ephexin4 protein mediates cell migration through a RhoG-dependent mechanism. PMID: 20679435
Subcellular Location Cytoplasm
Database Links

HGNC: 15515

KEGG: hsa:27237

STRING: 9606.ENSP00000367629

UniGene: Hs.87435
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