ARRDC1 Antibody

Code CSB-PA000933
Size US$100
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  • Western Blot analysis of Jurkat cells using Arrdc1 Polyclonal Antibody
  • Western Blot analysis of AD293 cells using Arrdc1 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
ARRDC1
Alternative Names
ARRD1_HUMAN antibody; ARRDC 1 antibody; ARRDC1 antibody; Arrestin domain containing 1 antibody; Arrestin domain containing protein 1 antibody; Arrestin domain-containing protein 1 antibody; MGC40555 antibody; OTTHUMP00000022707 antibody; OTTHUMP00000022709 antibody; RP11-48C7.5 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human Arrdc1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles. More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles. By participating in the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway.
Gene References into Functions
  1. The authors show that WWP1 changes the ubiquitination status of ARRDC1, suggesting that the arrestins may provide a platform for ubiquitination in PPXY-dependent budding. PMID: 21191027
Subcellular Location
Cell membrane.
Protein Families
Arrestin family
Database Links

HGNC: 28633

KEGG: hsa:92714

STRING: 9606.ENSP00000360475

UniGene: Hs.12999

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