ARSG Antibody

Code CSB-PA002150LA01HU
Size US$166
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Image
  • Western blot
    All lanes: ARSG antibody at 8µg/ml + Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 58 kDa
    Observed band size: 58 kDa

  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA002150LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA002150LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ARSG Polyclonal antibody
Uniprot No.
Target Names
ARSG
Alternative Names
Arsg antibody; ARSG_HUMAN antibody; Arylsulfatase G antibody; Arylsulfatase G precursor antibody; ASG antibody; KIAA1001 antibody; PRO1777 antibody; UNQ839 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Arylsulfatase G protein (17-525AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ARSG Antibody (Product code: CSB-PA002150LA01HU) is Non-conjugated. For ARSG Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA002150LB01HU ARSG Antibody, HRP conjugated ELISA
FITC CSB-PA002150LC01HU ARSG Antibody, FITC conjugated
Biotin CSB-PA002150LD01HU ARSG Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Displays arylsulfatase activity at acidic pH towards artificial substrates, such as p-nitrocatechol sulfate and also, but with a lower activity towards p-nitrophenyl sulfate and 4-methylumbelliferyl sulfate. Catalyzes the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.
Gene References into Functions
  1. This study provide further support for a role of ARSG variants in task-specific dystonia, especially writer's cramp. PMID: 25825126
  2. Genome-wide significance with musician's dystonia was observed for an intronic variant in the arylsulfatase G (ARSG) gene (rs11655081; P = 3.95 x 10(-9) ; odds ratio [OR], 4.33; 95% confidence interval [CI], 2.66-7.05). PMID: 24375517
  3. ARSG is differentially expressed, processed, and transported in tissues involving a membrane-associated pre-lysosomal precursor. PMID: 25135642
  4. Consistent genetic factors for ATP2B1, CSK, ARSG and CSMD1 were present, which have been shown to be associated with high blood pressure and hypertension in two Korean cohorts. PMID: 19960030
  5. molecular cloning and biochemical characterization of Arylsulfatase G [ARSG] PMID: 12461688
  6. Arylsulfatase G is a novel lysosomal sulfatase and its expression is tissue-specific with highest expression in liver, kidney, and pancreas PMID: 18283100

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Subcellular Location
Lysosome.
Protein Families
Sulfatase family
Tissue Specificity
Widely expressed, with very low expression in brain, lung, heart and skeletal muscle.
Database Links

HGNC: 24102

OMIM: 610008

KEGG: hsa:22901

STRING: 9606.ENSP00000407193

UniGene: Hs.437249

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