ASGR2 Antibody

Code CSB-PA002208LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA002208LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA002208LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA002208LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ASGR2 Polyclonal antibody
Uniprot No.
Target Names
ASGR2
Alternative Names
ASGR2; CLEC4H2; Asialoglycoprotein receptor 2; ASGP-R 2; ASGPR 2; C-type lectin domain family 4 member H2; Hepatic lectin H2; HL-2
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Asialoglycoprotein receptor 2 protein (63-286AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ASGR2 Antibody (Product code: CSB-PA002208LA01HU) is Non-conjugated. For ASGR2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA002208LB01HU ASGR2 Antibody, HRP conjugated ELISA
FITC CSB-PA002208LC01HU ASGR2 Antibody, FITC conjugated
Biotin CSB-PA002208LD01HU ASGR2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Gene References into Functions
  1. sH2a has the potential to be a uniquely sensitive and specific novel marker for liver fibrosis and function. PMID: 22096539
  2. trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid PMID: 12089159
Subcellular Location
Membrane; Single-pass type II membrane protein.
Tissue Specificity
Expressed exclusively in hepatic parenchymal cells.
Database Links

HGNC: 743

OMIM: 108361

KEGG: hsa:433

STRING: 9606.ENSP00000347140

UniGene: Hs.654440

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