ATG13 Antibody

Code CSB-PA560481
Size US$100
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  • Immunohistochemical analysis of paraffin-embedded Human Skeletal Muscle Tissue using ATG13 Rabbit pAb diluted at 1:200
  • Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using ATG13 Rabbit pAb diluted at 1:200
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Product Details

Uniprot No.
Target Names
ATG13
Alternative Names
ATG13 antibody; ATG13 autophagy related 13 homolog (S. cerevisiae) antibody; ATG13_HUMAN antibody; Autophagy related 13 antibody; Autophagy related protein 13 antibody; Autophagy-related protein 13 antibody; FLJ20698 antibody; KIAA0652 antibody; OTTHUMP00000233321 antibody; OTTHUMP00000233322 antibody; OTTHUMP00000233323 antibody; OTTHUMP00000233324 antibody; OTTHUMP00000233325 antibody; OTTHUMP00000233326 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant Protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Purification Method
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form
Liquid
Tested Applications
IHC, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:200
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Gene References into Functions
  1. Specific affinity of the LC3 isoforms to the Atg13 LC3-interacting region is required for proper autophagosome formation. PMID: 24290141
  2. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. PMID: 19597335
  3. The gene product is the functional homologue of yeast Atg13, and required for autophagy in mammalian cells. PMID: 18936157
Subcellular Location
Cytoplasm, cytosol. Preautophagosomal structure.
Protein Families
ATG13 family, Metazoan subfamily
Database Links

HGNC: 29091

OMIM: 615088

KEGG: hsa:9776

UniGene: Hs.127403

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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