ATG13 Antibody

Code CSB-PA012203LA01HU
Size US$166
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Image
  • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA012203LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA012203LA01HU at dilution of 1:100

  • Western Blot
    Positive WB detected in: A549 whole cell lysate
    All lanes: ATG13 antibody at 4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 57, 53, 45, 61 kDa
    Observed band size: 57 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ATG13 Polyclonal antibody
Uniprot No.
Target Names
ATG13
Alternative Names
ATG13 antibody; ATG13 autophagy related 13 homolog (S. cerevisiae) antibody; ATG13_HUMAN antibody; Autophagy related 13 antibody; Autophagy related protein 13 antibody; Autophagy-related protein 13 antibody; FLJ20698 antibody; KIAA0652 antibody; OTTHUMP00000233321 antibody; OTTHUMP00000233322 antibody; OTTHUMP00000233323 antibody; OTTHUMP00000233324 antibody; OTTHUMP00000233325 antibody; OTTHUMP00000233326 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Autophagy-related protein 13 protein (315-517AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ATG13 Antibody (Product code: CSB-PA012203LA01HU) is Non-conjugated. For ATG13 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA012203LB01HU ATG13 Antibody, HRP conjugated ELISA
FITC CSB-PA012203LC01HU ATG13 Antibody, FITC conjugated
Biotin CSB-PA012203LD01HU ATG13 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Gene References into Functions
  1. Specific affinity of the LC3 isoforms to the Atg13 LC3-interacting region is required for proper autophagosome formation. PMID: 24290141
  2. These data suggest that Atg101 is a novel Atg protein that functions together with ULK, Atg13 and FIP200. PMID: 19597335
  3. The gene product is the functional homologue of yeast Atg13, and required for autophagy in mammalian cells. PMID: 18936157
Subcellular Location
Cytoplasm, cytosol. Preautophagosomal structure.
Protein Families
ATG13 family, Metazoan subfamily
Database Links

HGNC: 29091

OMIM: 615088

KEGG: hsa:9776

UniGene: Hs.127403

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