ATP5L Antibody

Code CSB-PA002374GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ATP5L
Alternative Names
ATP synthase subunit g antibody; ATP synthase; H+ transporting; mitochondrial F1F0; subunit g antibody; ATP synthase; H+ transporting; mitochondrial Fo complex; subunit G antibody; ATP5L antibody; ATP5L_HUMAN antibody; ATPase subunit g antibody; F1Fo ATP synthase complex Fo membrane domain g subunit antibody; mitochondrial antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ATP5L
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
Gene References into Functions
  1. this study demonstrates that F1Fo ATP synthase can support general mitochondrial and cellular functions, working in extremely efficient 'energy saving' reverse mode and flexibly recruiting free radical detoxication and ATP producing / transporting pathways. PMID: 28189850
  2. Overexpression of miR-570-3p in platelets resulted in reduced levels of ATP5L mRNA and concomitant ATP loss. PMID: 27561077
Subcellular Location
Mitochondrion. Mitochondrion inner membrane.
Protein Families
ATPase g subunit family
Database Links

HGNC: 14247

OMIM: 617473

KEGG: hsa:10632

STRING: 9606.ENSP00000300688

UniGene: Hs.486360

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