ATP6V0D1 Antibody

Code CSB-PA002390GA01HU
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Product Details

Uniprot No. P61421
Target Names ATP6V0D1
Alternative Names 32 kDa accessory protein antibody; ATP6D antibody; ATP6DV antibody; ATP6V0D1 antibody; ATPase H+ transporting lysosomal (vacuolar proton pump) member D antibody; ATPase H+ transporting lysosomal 38kD V0 subunit d antibody; ATPase H+ transporting lysosomal 38kDa V0 subunit d1 antibody; ATPase H+ transporting lysosomal V0 subunit d1 antibody; H(+) transporting two sector ATPase subunit D antibody; p39 antibody; V ATPase 40 KDa accessory protein antibody; V ATPase AC39 subunit antibody; V ATPase subunit d 1 antibody; V ATPase subunit D antibody; V-ATPase 40 kDa accessory protein antibody; V-ATPase AC39 subunit antibody; V-ATPase subunit d 1 antibody; V-type proton ATPase subunit d 1 antibody; VA0D1_HUMAN antibody; Vacuolar ATP synthase subunit d 1 antibody; Vacuolar proton pump subunit d 1 antibody; VATX antibody; VMA 6 antibody; VMA6 antibody; VPATPD antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ATP6V0D1
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB,IHC
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Subunit of the integral membrane V0 complex of the lysosomal proton-transporting V-type ATPase (v-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium.
Gene References into Functions
  1. The secondary structures of d1 and d2 subunits were highly similar, but the relative stability against thermal stress was higher for d1 than d2. PMID: 24631925
  2. two adjacent enhancers inside the first intron of the neighboring (1.4 kb downstream) ATPase gene (ATP6V0D1) modulate the human AgRP promoter with profound spatiotemporal variation PMID: 19285986
  3. Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia PMID: 19165527
Subcellular Location Membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane.
Protein Families V-ATPase V0D/AC39 subunit family
Tissue Specificity Ubiquitous.
Database Links

HGNC: 13724

OMIM: 607028

KEGG: hsa:9114

STRING: 9606.ENSP00000290949

UniGene: Hs.106876

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