ATP6V0D1 Antibody

Datasheet

Code	CSB-PA004630
Size	US$119
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Image	Western Blot analysis of NIH-3T3 K562 cells using V-ATPase D1 Polyclonal Antibody
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Product Details
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Target Background

Product Details

Uniprot No.

P61421

Target Names

ATP6V0D1

Alternative Names

32 kDa accessory protein antibody; ATP6D antibody; ATP6DV antibody; ATP6V0D1 antibody; ATPase H+ transporting lysosomal (vacuolar proton pump) member D antibody; ATPase H+ transporting lysosomal 38kD V0 subunit d antibody; ATPase H+ transporting lysosomal 38kDa V0 subunit d1 antibody; ATPase H+ transporting lysosomal V0 subunit d1 antibody; H(+) transporting two sector ATPase subunit D antibody; p39 antibody; V ATPase 40 KDa accessory protein antibody; V ATPase AC39 subunit antibody; V ATPase subunit d 1 antibody; V ATPase subunit D antibody; V-ATPase 40 kDa accessory protein antibody; V-ATPase AC39 subunit antibody; V-ATPase subunit d 1 antibody; V-type proton ATPase subunit d 1 antibody; VA0D1_HUMAN antibody; Vacuolar ATP synthase subunit d 1 antibody; Vacuolar proton pump subunit d 1 antibody; VATX antibody; VMA 6 antibody; VMA6 antibody; VPATPD antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the Internal region of Human V-ATPase D1.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Subunit of the integral membrane V0 complex of the lysosomal proton-transporting V-type ATPase (v-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium.

Gene References into Functions

The secondary structures of d1 and d2 subunits were highly similar, but the relative stability against thermal stress was higher for d1 than d2. PMID: 24631925
two adjacent enhancers inside the first intron of the neighboring (1.4 kb downstream) ATPase gene (ATP6V0D1) modulate the human AgRP promoter with profound spatiotemporal variation PMID: 19285986
Using shotgun mass spectrometry, we found this protein differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia PMID: 19165527

Subcellular Location

Membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane.

Protein Families

V-ATPase V0D/AC39 subunit family

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 13724

OMIM: 607028

KEGG: hsa:9114

STRING: 9606.ENSP00000290949

UniGene: Hs.106876

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Oxidative Phosphorylation Synaptic vesicle cycle

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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