BBC3 Antibody

Code CSB-PA211852
Size US$297
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  • Western blot analysis of extracts from 293 and MCF-7 cells using Puma Antibody.

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BBC3 Polyclonal antibody
Uniprot No.
Target Names
BBC3
Alternative Names
BBC 3 antibody; Bbc3 antibody; BBC3_HUMAN antibody; BCL 2 binding component 3 antibody; Bcl-2-binding component 3 antibody; BCL2 binding component 3 antibody; JFY 1 antibody; JFY-1 antibody; JFY1 antibody; p53 up regulated modulator of apoptosis antibody; p53 up-regulated modulator of apoptosis antibody; p53 Upregulated Modulator of Apoptosis antibody; PUMA alpha antibody; PUMA/JFY1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Subcellular Location
Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release.
Protein Families
Bcl-2 family
Tissue Specificity
Ubiquitously expressed.
Database Links

HGNC: 17868

OMIM: 605854

KEGG: hsa:27113

UniGene: Hs.467020

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