BEX3 Antibody

Code CSB-PA015781ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA015781ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA015781ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BEX3 Polyclonal antibody
Uniprot No.
Target Names
BEX3
Alternative Names
Bex antibody; BEX3 antibody; BEX3_HUMAN antibody; Brain expressed X linked 3 (mouse) homolog antibody; brain expressed; X-linked 3 antibody; Brain-expressed X-linked gene 3 antibody; Brain-expressed X-linked protein 3 antibody; DXS6984E antibody; HGR74 antibody; NADE antibody; Nerve growth factor receptor (TNFRSF16) associated protein 1 antibody; Nerve growth factor receptor associated protein 1 antibody; Nerve growth factor receptor-associated protein 1 antibody; NGFR-associated protein 1 antibody; NGFRAP1 antibody; Ovarian granulosa cell 13.0 kDa protein HGR74 antibody; ovarian granulosa cell protein (13kD) antibody; Ovarian granulosa cell protein antibody; p75NTR associated cell death executor antibody; p75NTR-associated cell death executor antibody; Protein BEX3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein BEX3 protein (1-111AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
Gene References into Functions
  1. Results showed that BEX3 was overexpressed in nasopharyngeal carcinoma (NPC), and indicated a unique functional role of BEX3 in mediating the sensitivity of NPC cells to cisplatin. PMID: 28083995
  2. Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis PMID: 11830582
  3. suppresses cell growth in vivo, when expressed in cultured cells PMID: 12739005
  4. DRG-1 may contribute to the dopamine-induced cell growth, which is negatively regulated by NADE PMID: 16777077
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
BEX family
Tissue Specificity
Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
Database Links

HGNC: 13388

OMIM: 300361

KEGG: hsa:27018

STRING: 9606.ENSP00000299872

UniGene: Hs.448588

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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