NGFRAP1 Antibody

Code CSB-PA015781GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
BEX3
Alternative Names
Bex antibody; BEX3 antibody; BEX3_HUMAN antibody; Brain expressed X linked 3 (mouse) homolog antibody; brain expressed; X-linked 3 antibody; Brain-expressed X-linked gene 3 antibody; Brain-expressed X-linked protein 3 antibody; DXS6984E antibody; HGR74 antibody; NADE antibody; Nerve growth factor receptor (TNFRSF16) associated protein 1 antibody; Nerve growth factor receptor associated protein 1 antibody; Nerve growth factor receptor-associated protein 1 antibody; NGFR-associated protein 1 antibody; NGFRAP1 antibody; Ovarian granulosa cell 13.0 kDa protein HGR74 antibody; ovarian granulosa cell protein (13kD) antibody; Ovarian granulosa cell protein antibody; p75NTR associated cell death executor antibody; p75NTR-associated cell death executor antibody; Protein BEX3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human NGFRAP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. May play an important role in the pathogenesis of neurogenetic diseases.
Gene References into Functions
  1. Results showed that BEX3 was overexpressed in nasopharyngeal carcinoma (NPC), and indicated a unique functional role of BEX3 in mediating the sensitivity of NPC cells to cisplatin. PMID: 28083995
  2. Structure-function analysis of NADE: identification of regions that mediate nerve growth factor-induced apoptosis PMID: 11830582
  3. suppresses cell growth in vivo, when expressed in cultured cells PMID: 12739005
  4. DRG-1 may contribute to the dopamine-induced cell growth, which is negatively regulated by NADE PMID: 16777077
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
BEX family
Tissue Specificity
Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
Database Links

HGNC: 13388

OMIM: 300361

KEGG: hsa:27018

STRING: 9606.ENSP00000299872

UniGene: Hs.448588

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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