BPGM Antibody

Code CSB-PA002781ESR1HU
Size US$166
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Image
  • Western blot
    All lanes: BPGM antibody at 2.87µg/ml + Human placenta tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 30 kDa
    Observed band size: 30 kDa

  • Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA002781ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA002781ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BPGM Polyclonal antibody
Uniprot No.
Target Names
BPGM
Alternative Names
2 antibody; 2,3-bisphosphoglycerate mutase antibody; 2,3-bisphosphoglycerate mutase, erythrocyte antibody; 2,3-bisphosphoglycerate synthase antibody; 2,3-diphosphoglycerate mutase antibody; 3-bisphosphoglycerate mutase antibody; 3-bisphosphoglycerate synthase antibody; 3-diphosphoglycerate mutase antibody; Ab2 098 antibody; AI323730 antibody; AL022789 antibody; Bisphosphoglycerate mutase antibody; BPG dependent PGAM antibody; BPG-dependent PGAM antibody; Bpgm antibody; C86192 antibody; DPGM antibody; Erythrocyte 2,3 bisphosphoglycerate mutase antibody; erythrocyte antibody; PMGE_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Bisphosphoglycerate mutase protein (1-259AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity.
Gene References into Functions
  1. 1.94 A resolution X-ray structure of bisphosphoglycerate mutase is presented, focusing on the dynamic nature of key ligand-binding residues and their interaction with the inhibitor citrate PMID: 21045285
  2. bisphosphoglycerate mutase crystallographic structure PMID: 15258155
  3. analysis of histidine phosphorylation in human bisphosphoglycerate mutase PMID: 17052986
Involvement in disease
Bisphosphoglycerate mutase deficiency (BPGMD)
Protein Families
Phosphoglycerate mutase family, BPG-dependent PGAM subfamily
Tissue Specificity
Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level).
Database Links

HGNC: 1093

OMIM: 222800

KEGG: hsa:669

STRING: 9606.ENSP00000342032

UniGene: Hs.198365

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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