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BPGM Antibody

Datasheet
Code CSB-PA002781GA01HU
Size $600
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Product Details

Uniprot No.
P07738
Target Names
BPGM
Alternative Names
2 antibody; 2,3-bisphosphoglycerate mutase antibody; 2,3-bisphosphoglycerate mutase, erythrocyte antibody; 2,3-bisphosphoglycerate synthase antibody; 2,3-diphosphoglycerate mutase antibody; 3-bisphosphoglycerate mutase antibody; 3-bisphosphoglycerate synthase antibody; 3-diphosphoglycerate mutase antibody; Ab2 098 antibody; AI323730 antibody; AL022789 antibody; Bisphosphoglycerate mutase antibody; BPG dependent PGAM antibody; BPG-dependent PGAM antibody; Bpgm antibody; C86192 antibody; DPGM antibody; Erythrocyte 2,3 bisphosphoglycerate mutase antibody; erythrocyte antibody; PMGE_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human BPGM
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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BPGM Proteins

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Target Background

Function
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity.
Gene References into Functions
  1. 1.94 A resolution X-ray structure of bisphosphoglycerate mutase is presented, focusing on the dynamic nature of key ligand-binding residues and their interaction with the inhibitor citrate PMID: 21045285
  2. bisphosphoglycerate mutase crystallographic structure PMID: 15258155
  3. analysis of histidine phosphorylation in human bisphosphoglycerate mutase PMID: 17052986
Involvement in disease
Bisphosphoglycerate mutase deficiency (BPGMD)
Protein Families
Phosphoglycerate mutase family, BPG-dependent PGAM subfamily
Tissue Specificity
Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level).
Database Links

HGNC: 1093

OMIM: 222800

KEGG: hsa:669

STRING: 9606.ENSP00000342032

UniGene: Hs.198365

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