BPGM Antibody

Code CSB-PA002781ESR2HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot
    All lanes: BPGM antibody at 5.94µg/ml
    Lane 1: Human peripheral blood mononuclear cells
    Lane 2: Mouse liver tissue
    Lane 3: Human placenta tissue
    Lane 4: Hela whole cell lysate
    Lane 5: 293T whole cell lysate
    Lane 6: A549 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 30 kDa
    Observed band size: 30 kDa

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA002781ESR2HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) BPGM Polyclonal antibody
Uniprot No. P07738
Target Names BPGM
Alternative Names 2 antibody; 2,3-bisphosphoglycerate mutase antibody; 2,3-bisphosphoglycerate mutase, erythrocyte antibody; 2,3-bisphosphoglycerate synthase antibody; 2,3-diphosphoglycerate mutase antibody; 3-bisphosphoglycerate mutase antibody; 3-bisphosphoglycerate synthase antibody; 3-diphosphoglycerate mutase antibody; Ab2 098 antibody; AI323730 antibody; AL022789 antibody; Bisphosphoglycerate mutase antibody; BPG dependent PGAM antibody; BPG-dependent PGAM antibody; Bpgm antibody; C86192 antibody; DPGM antibody; Erythrocyte 2,3 bisphosphoglycerate mutase antibody; erythrocyte antibody; PMGE_HUMAN antibody
Raised in Rabbit
Species Reactivity Human, Mouse
Immunogen Recombinant Human Bisphosphoglycerate mutase protein (1-259AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.1) activity.
Gene References into Functions
  1. 1.94 A resolution X-ray structure of bisphosphoglycerate mutase is presented, focusing on the dynamic nature of key ligand-binding residues and their interaction with the inhibitor citrate PMID: 21045285
  2. bisphosphoglycerate mutase crystallographic structure PMID: 15258155
  3. analysis of histidine phosphorylation in human bisphosphoglycerate mutase PMID: 17052986
Involvement in disease Bisphosphoglycerate mutase deficiency (BPGMD)
Protein Families Phosphoglycerate mutase family, BPG-dependent PGAM subfamily
Tissue Specificity Expressed in red blood cells. Expressed in non-erythroid cells of the placenta; present in the syncytiotrophoblast layer of the placental villi at the feto-maternal interface (at protein level).
Database Links

HGNC: 1093

OMIM: 222800

KEGG: hsa:669

STRING: 9606.ENSP00000342032

UniGene: Hs.198365

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