BRINP3 Antibody

1. the association of serum OGN and FAM5C levels and muscle mass with bone mineral density (BMD), bone turnover markers, and the presence of vertebral fractures (VFs) in 156 postmenopausal women with type 2 diabetes mellitus, is reported. PMID: 27836731
2. Data show that all the six inflammation-related CpG-SNPs genotypes including IL1B rs16944, IL1R2 rs2071008, PLA2G7 rs9395208, FAM5C rs12732361, CD40 rs1800686, and CD36 rs2065666 were associated with coronary heart disease (CHD), suggesting an important role of inflammation in the risk of CHD. PMID: 27461004
3. FAM5C is a risk factor for cerebral infarction in type 2 diabetic patients. PMID: 26717922
4. The results demonstrated that FAM5C is an N-glycosylated protein, and N-glycosylation by UGGT1 is necessary for the secretion of FAM5C. PMID: 28351617
5. study provides evidence that the BRINP3 polymorphic variant rs1342913 and low level of BRINP3 expression are associated with peri-implantitis, independently from the presence of chronic periodontitis. PMID: 25887438
6. Data show that family with sequence similarity 5 member C protein FAM5C-positive endothelium expressed intercellular adhesion molecule-1 (ICAM-1) or vascular cell adhesion molecule-1 (VCAM-1). PMID: 25251368
7. Under expression of BRINP3 is associated with the pathogenesis of ulcerative colitis. PMID: 25171508
8. findings suggest a protective effect of T allele in women with a history of myocardial infarction (MI;) genotype of FAM5C rs10920501 explained about 7percent of variability of age of onset of coronary heart disease in women who have had an MI; FAM5C remains a gene of interest in a complex disease process PMID: 22013132
9. expression does not contribute to chronic periodontitis PMID: 22355820
10. Hypermethylated FAM5C and MYLK in serum are strongly associated with the development of gastric cancer and can be used as potential biomarkers for diagnosis and pre-warning. PMID: 22377736
11. FAM5C mRNA expression was significantly higher in aggressive periodontitis diseased versus healthy sites, and was found to be correlated to the IL-1beta, IL-17A, IL-4 and RANKL mRNA levels. PMID: 20383335
12. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
13. Observational study of gene-disease association. (HuGE Navigator) PMID: 20383335
14. BRINP3 is a mitochondrially localized protein that is selectively up-regulated in human gonadotropinomas; its actions to increase proliferation, migration, and invasion suggest it may play an important role in pituitary tumorigenesis PMID: 17138656
15. These data implicate FAM5C alleles in the risk of myocardial infarction and suggest further functional studies of FAM5C are required to identify the gene's contribution to atherosclerosis PMID: 18430236
16. Loss of FAM5C is associated with tongue squamous cell carcinoma. PMID: 19787213
17. Observational study of gene-disease association. (HuGE Navigator) PMID: 18430236
18. Genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 17903301

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HGNC: 22393

KEGG: hsa:339479

STRING: 9606.ENSP00000356432

UniGene: Hs.65765