C1QTNF1 Antibody

Datasheet
Code CSB-PA003646GA01HU
Size US$685
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Product Details

Uniprot No. Q9BXJ1
Target Names C1QTNF1
Alternative Names C1q and tumor necrosis factor related protein 1 antibody; C1QT1_HUMAN antibody; C1QTNF1 antibody; Complement C1q tumor necrosis factor related protein 1 antibody; Complement C1q tumor necrosis factor-related protein 1 antibody; CTRP 1 antibody; CTRP1 antibody; FLJ90694 antibody; G protein coupled receptor interacting protein 1 antibody; G protein-coupled receptor-interacting protein antibody; GIP antibody; ZSIG37 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human C1QTNF1
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB,IHC
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Gene References into Functions
  1. CTRP1 has a role in linking dysregulation of lipid metabolism and inflammatory responses in macrophages PMID: 27175610
  2. High serum CTRP1 level is associated with Type 2 diabetes mellitus. PMID: 28207876
  3. In cultured endothelial cells, treatment of CTRP1 led to increased permeability to fluorescent-labelled dextran and apparent formation of paracellular holes as observed after disturbed flow exposure, which was evidently reduced in the presence of a CTRP1-specific neutralizing antibody. PMID: 28625919
  4. Increased serum CTRP 1 levels were closely associated with the prevalence and severity of CAD, it might be regarded as a marker for myocardial infarction. PMID: 27169633
  5. the strong association of CTRP1 with insulin resistance in NAFLD PMID: 25767880
  6. The levels of circulating CTRP1 are associated with coronary artery disease in men. PMID: 24945145
  7. The variation of plasma CTRP-1 and IL-6 concentrations may play an important role in reflecting the degree of inflammation in CHD and the severity of coronary arterial atherosclerosis. PMID: 25635749
  8. Increased plasma CTRP1 was independently associated with type 2 diabetes. Profiling of plasma adipokines such as CTRP1 is particularly important to obtain a greater understanding of their contribution to the type 2 diabetic state. PMID: 24965225
  9. CTRP1 is a novel adipokine associated with type 2 diabetes mellitus in humans. PMID: 24827430
  10. CTRP1 level was significantly higher in subjects with metabolic syndrome compared to healthy subjects. PMID: 23000311
  11. The review describes the potential role of C1qTNF1 as an intracellular regulator of signal transduction PMID: 16386877
  12. molecular cloning, gene expression, and subcellular localization of GIP PMID: 12409230
  13. These findings indicate that CTRP1 expression may be associated with a low-grade chronic inflammation status in adipose tissues. PMID: 16806199
  14. CTRP1 enhances the production of aldosterone. CTRP1 was highly expressed in obese subjects as well as up-regulated in hypertensive patients, CTRP1 may be a newly identified molecular link between obesity and hypertension. PMID: 18171693
  15. CTRP1 may be considered a novel adipokine, providing an important framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. PMID: 18783346

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Subcellular Location Secreted
Database Links

HGNC: 14324

OMIM: 610365

KEGG: hsa:114897

STRING: 9606.ENSP00000340864

UniGene: Hs.201398

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