C5 Antibody

Datasheet
Code CSB-PA003995YA01PI
See More Details Free Antibody trial simple
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Uniprot No. P01032
Image
  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA003995YA01PI at dilution of 1:10

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Pig Complement C5a anaphylatoxin protein (1-74AA)
Raised in Rabbit
Species Reactivity Pig
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:10-1:100
Relevance Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis).
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Complement C5a anaphylatoxin, C5
Immunogen Species Pig
Research Area Immunology
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
Target Names C5
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
Subcellular Location Secreted
Database Links

STRING: 9823.ENSSSCP00000005908

UniGene: Ssc.21108

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